In vitro Activity of Six Antipseudomonal Agents against 84 Pseudomonas aeruginosa Strains Isolated from Dogs Determined by the E-Test (CROSBI ID 517901)
Prilog sa skupa u zborniku | sažetak izlaganja sa skupa | međunarodna recenzija
Podaci o odgovornosti
Šeol, Branka ; Naglić, Tomo ; Bedeković, Maja
engleski
In vitro Activity of Six Antipseudomonal Agents against 84 Pseudomonas aeruginosa Strains Isolated from Dogs Determined by the E-Test
Ciprofloxacin, enrofloxacin, gentamicin, cefipime ceftazidime and ticarcillin-clavulanic acid were tested by the E-test against 84 Pseudomonas aeruginosa strains. Ceftazidim was the most active agent with 100% of isolates having a MIC ≤ 8 mg/L (range 0.38 – 6). Ciprofloxacin and ticarcillin-clavulanic had similar activity 76% and 73% were inhibited by a MIC ≤ 1 mg/L (range 0.064 -1) and a MIC ≤ 64 mg/L (range 4 -64) respectively. Cefipime inhibited 50% of tested strains with a MIC ≤ 8 mg/L of (range 0.75 – 8). Gentamicin was the least active with 42% of P. aeruginosa isolates having a MIC ≤ 4 (range 0.125 – 16). Interpretative criteria for enrofloxacin are provide by the CLSI veterinary guidelines (M31-A2, 2002) and refer to the specific animal being treated. The CLSI guidelines state that for canine and feline Gram negative enteritic bacilli and other susceptible microorganisms, the breakpoints are S≤ 0.5, F= 1-2 and R ≥ 4, where F indicates the availability of FDA-approved labeling and those microorganisms should be considered susceptible if dosing modifications found in the package insert are applied. According to CLSI none of 84 tested strains were susceptible to enrofloxacin, 57% (48 strains) were resistant with a MIC range 3 – 32 mg/L and 43% (36 strains) having a MIC range 0.75 – 3mg/L, were ranged as category F.
antipseudomonal agents; Pseudomonas aeruginosa; dogs; E-test
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Podaci o prilogu
O14-014-x.
2006.
objavljeno
Podaci o matičnoj publikaciji
Cesar 2006. Book of Abstracts
Dwornicek i sur.
Bratislava: Dwornicek i sur.
Podaci o skupu
CESAR 2006. Central European Symposium on Antimicrobial Resistance
predavanje
18.06.2006-21.06.2006
Vysoké Tatry, Slovačka