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Pregled bibliografske jedinice broj: 251098

Association of Two Genetic Variations of Lipoprotein Lipase, S447X and Hind III, with Coronary Artery Disease and Hypertriglyceridemia


Pašalić, Daria; Ferenčak, Goran; Gršković, Branka; Šesto, Mihajlo; Stavljenić-Rukavina, Ana
Association of Two Genetic Variations of Lipoprotein Lipase, S447X and Hind III, with Coronary Artery Disease and Hypertriglyceridemia // Collegium Anthroplogicum, 30 (2006), 3; 549-554 (međunarodna recenzija, članak, znanstveni)


CROSBI ID: 251098 Za ispravke kontaktirajte CROSBI podršku putem web obrasca

Naslov
Association of Two Genetic Variations of Lipoprotein Lipase, S447X and Hind III, with Coronary Artery Disease and Hypertriglyceridemia

Autori
Pašalić, Daria ; Ferenčak, Goran ; Gršković, Branka ; Šesto, Mihajlo ; Stavljenić-Rukavina, Ana

Izvornik
Collegium Anthroplogicum (0350-6134) 30 (2006), 3; 549-554

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
coronary artery disease; hypertriglyceridemia; lipoprotein lipase; polymorphism; Croatia

Sažetak
This study was performed to assess the effect of the S447X and Hind III lipoprotein lipase gene polymorphisms on development of coronary artery disease and hypertriglyceridemia. The study included 132 patients and 98 healthy control subjects of Croatian descent. The lipoprotein lipase S447X polymorphism was associated with coronary artery disease and hypertriglyceridemia, as indicated by the lower frequency of S447 allele in the patient group (p=0.005) and odds ratio (O.R=0.40, p=0.006). The patient and control groups also showed a significant difference in the distribution of Hind III/S447X genotype combinations (p=0.013). There were no significant associations with lipid parameters for any genotype or genotype combination in the patient group. Frequencies of the S447X polymorphism and S447X/Hind III combinations differed between the CAD/TG and control group, thus these polymorphisms may be associated with CAD and hypertriglyceridemia.

Izvorni jezik
Engleski

Znanstvena područja
Matematika, Arhitektura i urbanizam, Brodogradnja



POVEZANOST RADA


Projekti:
0108247

Ustanove:
Medicinski fakultet, Zagreb


Citiraj ovu publikaciju

Pašalić, Daria; Ferenčak, Goran; Gršković, Branka; Šesto, Mihajlo; Stavljenić-Rukavina, Ana
Association of Two Genetic Variations of Lipoprotein Lipase, S447X and Hind III, with Coronary Artery Disease and Hypertriglyceridemia // Collegium Anthroplogicum, 30 (2006), 3; 549-554 (međunarodna recenzija, članak, znanstveni)
Pašalić, D., Ferenčak, G., Gršković, B., Šesto, M. & Stavljenić-Rukavina, A. (2006) Association of Two Genetic Variations of Lipoprotein Lipase, S447X and Hind III, with Coronary Artery Disease and Hypertriglyceridemia. Collegium Anthroplogicum, 30 (3), 549-554.
@article{article, year = {2006}, pages = {549-554}, keywords = {coronary artery disease, hypertriglyceridemia, lipoprotein lipase, polymorphism, Croatia}, journal = {Collegium Anthroplogicum}, volume = {30}, number = {3}, issn = {0350-6134}, title = {Association of Two Genetic Variations of Lipoprotein Lipase, S447X and Hind III, with Coronary Artery Disease and Hypertriglyceridemia}, keyword = {coronary artery disease, hypertriglyceridemia, lipoprotein lipase, polymorphism, Croatia} }
@article{article, year = {2006}, pages = {549-554}, keywords = {coronary artery disease, hypertriglyceridemia, lipoprotein lipase, polymorphism, Croatia}, journal = {Collegium Anthroplogicum}, volume = {30}, number = {3}, issn = {0350-6134}, title = {Association of Two Genetic Variations of Lipoprotein Lipase, S447X and Hind III, with Coronary Artery Disease and Hypertriglyceridemia}, keyword = {coronary artery disease, hypertriglyceridemia, lipoprotein lipase, polymorphism, Croatia} }

Časopis indeksira:


  • Current Contents Connect (CCC)
  • Web of Science Core Collection (WoSCC)
    • Social Science Citation Index (SSCI)
    • SCI-EXP, SSCI i/ili A&HCI
  • Scopus
  • MEDLINE





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