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Metabolism of Anabolic Steroids by Recombinant Human Cytochrome P450 Enzymes (CROSBI ID 469358)

Prilog sa skupa u zborniku | izvorni znanstveni rad

Rendić, Slobodan ; Nolteernsting, Eckhard ; Schänzer, Wilhelm Metabolism of Anabolic Steroids by Recombinant Human Cytochrome P450 Enzymes // Recent Advances in Doping Analysis (6), Proceedings of the Manfred Donike Workshop / Schänzer, Wilhelm ; Gayer, Hans ; Gotzmann, Andrea et al. (ur.). Köln: Sport und Buch Strauss, 1999. str. 81-95-x

Podaci o odgovornosti

Rendić, Slobodan ; Nolteernsting, Eckhard ; Schänzer, Wilhelm

engleski

Metabolism of Anabolic Steroids by Recombinant Human Cytochrome P450 Enzymes

In the present work different formats of human recombinant CYP3A4, CYP2B6 and CYP2C9 have been investigated for in vitro study of metabolism of anabolic steroids. Enzyme formats used were microsomes prepared from insect cells expressing human CYP enzymes and purified recombinant human CYP enzymes. The steroids studied were testosterone, 17alpha-methyltestosterone, metandienone, boldenone and 4-chloro-1,2-dehydro-17alpha-methyltestosterone.

Cytochromes P450; CYP; steroids; hydroxylation; recombinant enzymes

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Podaci o prilogu

81-95-x.

1999.

objavljeno

Podaci o matičnoj publikaciji

Recent Advances in Doping Analysis (6), Proceedings of the Manfred Donike Workshop

Schänzer, Wilhelm ; Gayer, Hans ; Gotzmann, Andrea ; Mareck-Engelke

Köln: Sport und Buch Strauss

Podaci o skupu

Nepoznat skup

predavanje

29.02.1904-29.02.2096

Povezanost rada

Farmacija