Metabolism of Anabolic Steroids by Recombinant Human Cytochrome P450 Enzymes (CROSBI ID 469358)
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Podaci o odgovornosti
Rendić, Slobodan ; Nolteernsting, Eckhard ; Schänzer, Wilhelm
engleski
Metabolism of Anabolic Steroids by Recombinant Human Cytochrome P450 Enzymes
In the present work different formats of human recombinant CYP3A4, CYP2B6 and CYP2C9 have been investigated for in vitro study of metabolism of anabolic steroids. Enzyme formats used were microsomes prepared from insect cells expressing human CYP enzymes and purified recombinant human CYP enzymes. The steroids studied were testosterone, 17alpha-methyltestosterone, metandienone, boldenone and 4-chloro-1,2-dehydro-17alpha-methyltestosterone.
Cytochromes P450; CYP; steroids; hydroxylation; recombinant enzymes
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Podaci o prilogu
81-95-x.
1999.
objavljeno
Podaci o matičnoj publikaciji
Recent Advances in Doping Analysis (6), Proceedings of the Manfred Donike Workshop
Schänzer, Wilhelm ; Gayer, Hans ; Gotzmann, Andrea ; Mareck-Engelke
Köln: Sport und Buch Strauss
Podaci o skupu
Nepoznat skup
predavanje
29.02.1904-29.02.2096