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Pregled bibliografske jedinice broj: 249688

Comparison of immunogenicity of recombinant and plasma derived hepatitis B antigen in guinea pigs


Valinger, Zdenka; Treščec, Anđa; Tomašić, Jelka
Comparison of immunogenicity of recombinant and plasma derived hepatitis B antigen in guinea pigs // Vaccine, 8 (1990), 585 - 589 (međunarodna recenzija, članak, znanstveni)


CROSBI ID: 249688 Za ispravke kontaktirajte CROSBI podršku putem web obrasca

Naslov
Comparison of immunogenicity of recombinant and plasma derived hepatitis B antigen in guinea pigs

Autori
Valinger, Zdenka ; Treščec, Anđa ; Tomašić, Jelka

Izvornik
Vaccine (0264-410X) 8 (1990); 585 - 589

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
HBsAg; immunoassay; guinea pig; plasma-derived; recombinant

Sažetak
Four different preparations of hepatitis B antigen (HBsAg) were tested in parallel with respect to their ability to elicit anti-HBs in guinea pigs. We compared the effect of low doses od human plasma derived and recombinant HBsAg in purified forms or prepared as vaccines, respectively. The highest titre of anti-HBs developed was detected in guinea pigs immunized with plasma derived HBsAg, followed by the response in animals immunized with plasma derived vaccine. Purified recombinant antigen and recombinant vaccine exhibited poor immunogenicity compared with plasma derived antigen preparations.

Izvorni jezik
Engleski

Znanstvena područja
Kemija, Temeljne medicinske znanosti, Biotehnologija



POVEZANOST RADA


Projekti:
1-07-044

Ustanove:
Imunološki zavod d.d.


Citiraj ovu publikaciju:

Valinger, Zdenka; Treščec, Anđa; Tomašić, Jelka
Comparison of immunogenicity of recombinant and plasma derived hepatitis B antigen in guinea pigs // Vaccine, 8 (1990), 585 - 589 (međunarodna recenzija, članak, znanstveni)
Valinger, Z., Treščec, A. & Tomašić, J. (1990) Comparison of immunogenicity of recombinant and plasma derived hepatitis B antigen in guinea pigs. Vaccine, 8, 585 - 589.
@article{article, author = {Valinger, Zdenka and Tre\v{s}\v{c}ec, An\dja and Toma\v{s}i\'{c}, Jelka}, year = {1990}, pages = {585 - 589}, keywords = {HBsAg, immunoassay, guinea pig, plasma-derived, recombinant}, journal = {Vaccine}, volume = {8}, issn = {0264-410X}, title = {Comparison of immunogenicity of recombinant and plasma derived hepatitis B antigen in guinea pigs}, keyword = {HBsAg, immunoassay, guinea pig, plasma-derived, recombinant} }
@article{article, author = {Valinger, Zdenka and Tre\v{s}\v{c}ec, An\dja and Toma\v{s}i\'{c}, Jelka}, year = {1990}, pages = {585 - 589}, keywords = {HBsAg, immunoassay, guinea pig, plasma-derived, recombinant}, journal = {Vaccine}, volume = {8}, issn = {0264-410X}, title = {Comparison of immunogenicity of recombinant and plasma derived hepatitis B antigen in guinea pigs}, keyword = {HBsAg, immunoassay, guinea pig, plasma-derived, recombinant} }

Časopis indeksira:


  • Current Contents Connect (CCC)
  • Web of Science Core Collection (WoSCC)
    • SCI-EXP, SSCI i/ili A&HCI
  • Scopus
  • MEDLINE





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