Učestalost antikardiolipinskih, antinuklearnih i anti-beta2 glikoproteinskih I protutijela u djece s epilepsijom (CROSBI ID 517449)
Prilog sa skupa u zborniku | sažetak izlaganja sa skupa | domaća recenzija
Podaci o odgovornosti
Markić, Joško ; Meštrović, Marija ; Valić, Ivan ; Sapunar, Ada ; Bošnjak, Nada
hrvatski
Učestalost antikardiolipinskih, antinuklearnih i anti-beta2 glikoproteinskih I protutijela u djece s epilepsijom
A high prevalence of epilepsy in specific immunological diseases suggests that the immune system may play a role in the pathogenesis of epilepsy. Many studies have suggested that aberrations of the immunological system may be associated with epilepsy. This study determined the presence of anticardiolipin antibodies (aCL), antinuclear antibodies (ANA) and anti-b2-glycoprotein I antibodies (anti-b2-GPI) in 40 children with epilepsy and 38 healthy subjects. We found aCL to be positive in 3 patients, and anti-b2-GPI in 1 patient. In control group they were negative. ANA antibodies were negative in both groups. Duration of epilepsy < 1 year was recorded in all three patients with positive aCL. However, no statistically significant difference was found in the presence of aCL, ANA, and anti-b2-GPI between patients and control subjects. There was no statistically significant correlation between age, sex, age at onset of epilepsy, duration of epilepsy, seizure frequency or specific antiepileptic medications with the presence of any measured antibodies. When epileptic patients were subdivided according to their type of seizure, we found no significant difference in the distribution of antibodies.
epilepsija; antinuklearna antitijela; antikardiolipinska antitijela; anti-beta2-glikoprotein I antitijela
nije evidentirano
engleski
Frequency of Anticardiolipin, Antinuclear and anti-betha2 Glycoprotein I Antibodies in Children with Epilepsy
A high prevalence of epilepsy in specific immunological diseases suggests that the immune system may play a role in the pathogenesis of epilepsy. Many studies have suggested that aberrations of the immunological system may be associated with epilepsy. This study determined the presence of anticardiolipin antibodies (aCL), antinuclear antibodies (ANA) and anti-b2-glycoprotein I antibodies (anti-b2-GPI) in 40 children with epilepsy and 38 healthy subjects. We found aCL to be positive in 3 patients, and anti-b2-GPI in 1 patient. In control group they were negative. ANA antibodies were negative in both groups. Duration of epilepsy < 1 year was recorded in all three patients with positive aCL. However, no statistically significant difference was found in the presence of aCL, ANA, and anti-b2-GPI between patients and control subjects. There was no statistically significant correlation between age, sex, age at onset of epilepsy, duration of epilepsy, seizure frequency or specific antiepileptic medications with the presence of any measured antibodies. When epileptic patients were subdivided according to their type of seizure, we found no significant difference in the distribution of antibodies.
epilepsy; antinuclear antibodies; anticardiolipin antibodies; anti-betha2-glycoprotein I antibodies
nije evidentirano
nije evidentirano
nije evidentirano
nije evidentirano
nije evidentirano
nije evidentirano
Podaci o prilogu
89-89-x.
2006.
objavljeno
Podaci o matičnoj publikaciji
Neurologia Croatica (Vol. 55 Suppl. 1)
Hodoba, Danilo D. ; Cvitanović-Šojat, Ljerka
Zagreb: Klinika za neurologiju Kliničkoga bolničkog centra Zagreb
Podaci o skupu
VII. hrvatski simpozij o epilepsiji
poster
28.05.2006-01.06.2006
Pula, Hrvatska