engleski

Qualitative Glandular Cervical Score as a Potential New Sonomorphological Parameter in Screening for Preterm Delivery

Objective: To compare cervical length (CL) measurement and qualitative glandular cervical score (QGCS), assessed by transvaginal ultrasound in mid trimester, regarding the prediction of preterm delivery (PTD) in low-risk population. Study design: Prospective cohort study of 278 low-risk, asymptomatic, nulliparous women with singleton pregnancies. Cervical length and QGCS were evaluated between 16 and completed 23 weeks. Cervical length 24 mm or less was defined as shortened. The parameters evaluated in QGCS were: cervical mucus area and deepest invasion of cervical glands. Qualitative glandular cervical score 1 or less was defined as low. Results: Shortened CL was found in 6.1% (17/278) whereas the low QGCS was found in 5.7% (16/278). The incidence of PTD before completed 34 weeks was 2.1% (6/278) and between 34 - 37 weeks 3.2% (9/278). Low QGCS in comparison with shortened CL had better sensitivity (83.3% vs. 66.6%) for PTD before completed 34 weeks as well as better sensitivity (55.5% vs. 22.2%) for PTD between 34 – 37 weeks. Positive predictive value was 31.2% vs. 23.5% for delivery before completed 34 weeks and 31.2% vs. 11.7% between 34 – 37 weeks. Conclusion: Qualitative Glandular Cervical Score has the same if not better accuracy in comparison with CL measurement regarding the prediction of PTD.

Transvaginal sonography; mid trimester; cervical length; cervical mucus area; cervical gland invasion; preterm delivery

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