engleski

Synthesis of Novel, Potentially Biologically Active Dibenzosuberone Derivatives

Novel representatives of the important group of biologically active dibenzosuberone derivatives were prepared, 3, 7-dibromo-5-(dimethylaminoethyl-oxyimino)-10, 11-dihydro-5H-dibenzo[a, d]cyclohepta-1, 4-diene (1), 3, 7-dibromo-5-(3-dimethylaminopropylidene)-10, 11-dihydro-5H-dibenzo[a, d]cycloheptene (2) and 1, 7-dibromo-5-(3-dimethylaminopropylidene)-10, 11-dihydro-5H-dibenzo[a, d]cycloheptene (3). These compounds are potential members of tricyclic antidepressants (TCAs), still in many countries the most frequently prescribed antidepressants.

Dibenzosuberone ; tricyclic antidepressants ; bromination ; amitryptiline ; noxiptiline

nije evidentirano