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Synthesis of Novel, Potentially Biologically Active Dibenzosuberone Derivatives


Merkaš, Sonja; Litvić, Mladen; Cepanec, Ivica; Vinković, Vladimir
Synthesis of Novel, Potentially Biologically Active Dibenzosuberone Derivatives // Molecules, 10 (2005), 12; 1429-1437 doi:10.3390/10121429 (međunarodna recenzija, članak, znanstveni)


Naslov
Synthesis of Novel, Potentially Biologically Active Dibenzosuberone Derivatives

Autori
Merkaš, Sonja ; Litvić, Mladen ; Cepanec, Ivica ; Vinković, Vladimir

Izvornik
Molecules (1420-3049) 10 (2005), 12; 1429-1437

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
Dibenzosuberone ; tricyclic antidepressants ; bromination ; amitryptiline ; noxiptiline

Sažetak
Novel representatives of the important group of biologically active dibenzosuberone derivatives were prepared, 3, 7-dibromo-5-(dimethylaminoethyl-oxyimino)-10, 11-dihydro-5H-dibenzo[a, d]cyclohepta-1, 4-diene (1), 3, 7-dibromo-5-(3-dimethylaminopropylidene)-10, 11-dihydro-5H-dibenzo[a, d]cycloheptene (2) and 1, 7-dibromo-5-(3-dimethylaminopropylidene)-10, 11-dihydro-5H-dibenzo[a, d]cycloheptene (3). These compounds are potential members of tricyclic antidepressants (TCAs), still in many countries the most frequently prescribed antidepressants.

Izvorni jezik
Engleski

Znanstvena područja
Kemija



POVEZANOST RADA


Projekt / tema
0098051
0098053

Ustanove
Institut "Ruđer Bošković", Zagreb

Profili:

Avatar Url Ivica Cepanec (autor)

Avatar Url Mladen Litvić (autor)

Avatar Url Sonja Merkaš (autor)

Avatar Url Vladimir Vinković (autor)

Citiraj ovu publikaciju

Merkaš, Sonja; Litvić, Mladen; Cepanec, Ivica; Vinković, Vladimir
Synthesis of Novel, Potentially Biologically Active Dibenzosuberone Derivatives // Molecules, 10 (2005), 12; 1429-1437 doi:10.3390/10121429 (međunarodna recenzija, članak, znanstveni)
Merkaš, S., Litvić, M., Cepanec, I. & Vinković, V. (2005) Synthesis of Novel, Potentially Biologically Active Dibenzosuberone Derivatives. Molecules, 10 (12), 1429-1437 doi:10.3390/10121429.
@article{article, year = {2005}, pages = {1429-1437}, DOI = {10.3390/10121429}, keywords = {Dibenzosuberone, tricyclic antidepressants, bromination, amitryptiline, noxiptiline}, journal = {Molecules}, doi = {10.3390/10121429}, volume = {10}, number = {12}, issn = {1420-3049}, title = {Synthesis of Novel, Potentially Biologically Active Dibenzosuberone Derivatives}, keyword = {Dibenzosuberone, tricyclic antidepressants, bromination, amitryptiline, noxiptiline} }

Časopis indeksira:


  • Current Contents Connect (CCC)
  • Web of Science Core Collection (WoSCC)
    • Science Citation Index Expanded (SCI-EXP)
    • SCI-EXP, SSCI i/ili A&HCI
  • Scopus
  • MEDLINE


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