engleski

Yeast Gal4 - A transcriptional paradigm revisited

Over the last two decades the yeast Gal4 protein has served as a model for studying transcriptional activation in eukaryotes. Many of the properties of transcriptional regulation first demonstrated for Gal4 have since been shown to be reiterated in the function of numerous other eukaryotic transcriptional regulators. In this review we present an updated account of Gal4 function taking into account the advent of new technologies recently applied to the study of the GAL network.

Gal4; transcription; RNA polymerase II; yeast

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