engleski

Tween 80-solubilized Newcastle disease virus prepared as a water-in-oil-in-water vaccine

Antigenic surface subunits of Newcastle disease virus were obtained by solubilization with non-ionic detergent Tween 80. Viral subunit were prepared in the form of a water-in-oil-in-water (WOW) vaccine with low oil content. The solubilized NDV, administered alone or built in a tetravalent vaccine, completely protected primary vaccinated chickens and generated long-lasting high level of NDV neutralizing antibodies in revaccinated pullets.

chicken; inactivated vaccine; laying hens; Newcastle disease; polyvalent vaccine; pullet; split-off vaccine; water-in-oil-in-water vaccine

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