Paraneoplastični sindrom povezan s antifosfolipidnim protutijelama (CROSBI ID 119322)
Prilog u časopisu | ostalo
Podaci o odgovornosti
Krmpotić, Dijana ; Čikeš, Nada ; Krmpotić, Pavao
hrvatski
Paraneoplastični sindrom povezan s antifosfolipidnim protutijelama
In patients with malignant tumour signs and symptoms develop that cannot be explained on the basis of the mass effect produced by either primary tumour or its metastases, production of a hormone associated with tissue type giving rise to the malignant tumour, or patients' immune status. These symptom complexes are known as paraneoplastic syndrome. It is known that the patients with malignant tumours are prone to develop venous thromboembolism in any stage of their disease. It is suggested that thromboembolic manifestations in cancer patients may be part of the secondary antiphospholipid syndrome (APS) and an example of the paraneoplastic autoimmunity, eg., paraneoplastic syndrome. Antiphospholipid antibodies (APA), e.g., anticardiolipin antibodies (ACA) and circulating lupus anticoagulant (LAC) are known to predispose to venous and arterial thromboses. The growing number of clinical reports on the association of APA and malignant tumours suggests that APA may be one of contributory factors in the paraneoplastic thromboembolism occurring in malignancy.
paraneoplastički sindrom; antifosfolipidna protutijela
nije evidentirano
engleski
Paraneoplastic syndrome associated with antiphospholipid antibodies
nije evidentirano
paraneoplastic syndromes; antiphospholipid antibodies
nije evidentirano
Podaci o izdanju
126 (5-6)
2004.
155-60-x
objavljeno
0024-3477
1849-2177