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Pregled bibliografske jedinice broj: 229289

Salivary and serum interleukin 6 and basic fibroblast growth factor levels in patients with oral squamous cell carcinoma


Vučičević Boras, Vanja; Čikeš, Nada; Lukač, J; Virag, Mišo; Cekić-Arambašin, Ana
Salivary and serum interleukin 6 and basic fibroblast growth factor levels in patients with oral squamous cell carcinoma // Minerva Stomatologica, 54 (2005), 10; 569-73 (međunarodna recenzija, članak, znanstveni)


CROSBI ID: 229289 Za ispravke kontaktirajte CROSBI podršku putem web obrasca

Naslov
Salivary and serum interleukin 6 and basic fibroblast growth factor levels in patients with oral squamous cell carcinoma

Autori
Vučičević Boras, Vanja ; Čikeš, Nada ; Lukač, J ; Virag, Mišo ; Cekić-Arambašin, Ana

Izvornik
Minerva Stomatologica (0026-4970) 54 (2005), 10; 569-73

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
interleukin 6; basic fibroblast growth factor; oral squamous cell carcinoma

Sažetak
AIM: A role of various cytokines has been implicated in the pathogenesis of many carcinomas, and albeit the role of interleukin 6 (IL-6) and basic fibroblast growth factor (bFGF) in sera has been studied in patients with oral carcinomas, data upon salivary IL-6 and bFGF are lacking. The aim of this study was to evaluate levels of IL-6 and bFGF in the saliva and serum of patients with oral squamous cell carcinoma. METHODS: Salivary and serum IL-6 and bFGF were evaluated in a group of 33 patients (28 men, 5 women) with oral squamous cell carcinoma (OSCC), age range 40-73 years , mean 54.05 years. Control group consisted of 23 healhy participants, mean age 25 years. RESULTS: Serum IL-6 and bFGF levels were not significantly different between patients with OSCC and healthy controls. Elevated levels of salivary IL-6 and bFGF in patients with OSCC when compared to the healthy controls were found (p<0.001). CONCLUSIONS: The conclusion is drawn that higher levels of salivary IL-6 and bFGF in patients with OSCC might originate from the local production, probably from carcinoma cells.

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti, Dentalna medicina



POVEZANOST RADA


Projekti:
0108190

Ustanove:
Stomatološki fakultet, Zagreb,
Medicinski fakultet, Zagreb


Citiraj ovu publikaciju

Vučičević Boras, Vanja; Čikeš, Nada; Lukač, J; Virag, Mišo; Cekić-Arambašin, Ana
Salivary and serum interleukin 6 and basic fibroblast growth factor levels in patients with oral squamous cell carcinoma // Minerva Stomatologica, 54 (2005), 10; 569-73 (međunarodna recenzija, članak, znanstveni)
Vučičević Boras, V., Čikeš, N., Lukač, J., Virag, M. & Cekić-Arambašin, A. (2005) Salivary and serum interleukin 6 and basic fibroblast growth factor levels in patients with oral squamous cell carcinoma. Minerva Stomatologica, 54 (10), 569-73.
@article{article, year = {2005}, pages = {569-73}, keywords = {interleukin 6, basic fibroblast growth factor, oral squamous cell carcinoma}, journal = {Minerva Stomatologica}, volume = {54}, number = {10}, issn = {0026-4970}, title = {Salivary and serum interleukin 6 and basic fibroblast growth factor levels in patients with oral squamous cell carcinoma}, keyword = {interleukin 6, basic fibroblast growth factor, oral squamous cell carcinoma} }
@article{article, year = {2005}, pages = {569-73}, keywords = {interleukin 6, basic fibroblast growth factor, oral squamous cell carcinoma}, journal = {Minerva Stomatologica}, volume = {54}, number = {10}, issn = {0026-4970}, title = {Salivary and serum interleukin 6 and basic fibroblast growth factor levels in patients with oral squamous cell carcinoma}, keyword = {interleukin 6, basic fibroblast growth factor, oral squamous cell carcinoma} }

Časopis indeksira:


  • Scopus
  • MEDLINE





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