Naslov
Latent hazard in pc and bph patients referred to antiandrogens : pc aggressiveness and ne differentiation

Autori
Tarle, Marko ; Petek, Tarnik, Iva ; Novosel, Sunčica ; Ahel, Zaky ; Kusić, Zvonko

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, znanstveni

Izvornik
Abstracts of the 7th international conference of anticancer research ; u: Anticancer research 24 (2004) (5d) 3393-3698 ; Abst.No. 501 / - , 2004, 3648-

Skup
International conference of anticancer research (7 ; 2004)

Mjesto i datum
Krf, Grčka, 25.10.2004. - 30.10.2004

Vrsta sudjelovanja
Poster

Vrsta recenzije
Međunarodna recenzija

Ključne riječi
antiandrogen treatment; BPH patients

Sažetak
Antiandrogen treatment of BPH often involves finasteride therapy yielding intraprostatic DHT deficiency. We reported that prolonged antiandrogen therapy may provoke the acquisition of neuroendocrine (NE) activity within the prostate. NE differentiation is a risk factor for the development of an aggressive prostate cancer. This study was undertaken to elucidate the cancer development hazard in BPH patients (pts) treated with finasteride.

Izvorni jezik
Engleski

Znanstvena područja
Temeljne medicinske znanosti, Kliničke medicinske znanosti

POVEZANOST RADA