The role of dopamine in the formation of gastric ulcers in rats (CROSBI ID 118711)
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Podaci o odgovornosti
Sikirić, Predrag ; Geber, Juraj ; Suchanek, Ernest ; Ivanović, Drago ; Gjuriš, Veljko ; Aleksić, Jelena ; Reić, Petar ; Marović, Anton
engleski
The role of dopamine in the formation of gastric ulcers in rats
A single dose of the dopamine agonists L-dopa, bromocriptine or apomorphine produced a protective effect by significantly shortening of the length of stomach ulcerations. A single dose of the dopamine antagonists haloperidol, sulpiride or domperidone potentiated the ulcerogenic effect by extending the length of stomach ulcerations. These results point to the fact that dopamine is involved in the rise and development of experimental stomach ulcers.
Dopamine agonists; Dopamine antagonists; Gastric ulcer
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