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Pregled bibliografske jedinice broj: 2229

Stem cell antigen 2 expression in adult and developing mice


Antica, Mariastefania; Wu, Li; Scollay, Roland
Stem cell antigen 2 expression in adult and developing mice // Immunology letters, 55 (1997), 1; 47-51 (međunarodna recenzija, članak, znanstveni)


Naslov
Stem cell antigen 2 expression in adult and developing mice

Autori
Antica, Mariastefania ; Wu, Li ; Scollay, Roland

Izvornik
Immunology letters (0165-2478) 55 (1997), 1; 47-51

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
Development; sca-2/tsa-1 antigen; stem cells; T-lymphocytes; precursor cells

Sažetak
Stem cell antigen 2 (Sca-2) expression can distinguish the most immature T-lymphocyte precursors in the thymus from the hemopoietic stem cells. Sequence analysis of the Sca-2 protein showed that Sca-2 is a glycosylphosphatidylinositol (GPI) anchored molecule that shares some characteristics with the members of the Ly-6 multigene family, and that it is the same as the thymic shared antigen-1 (TSA-1). Here we extend these studies and critically reassess the expression of the Sca-2/TSA-1 antigen in hematopoietic tissues of adult and developing mice. With more sensitive methods we show that the distribution of Sca-2/TSA-1 differs from existing reports. We find especially high expression of Sca-2/TSA1 at day 14 of fetal development. (C) 1997 Elsevier Science B.V. [References: 22]

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti



POVEZANOST RADA


Projekt / tema
00981101

Ustanove
Institut "Ruđer Bošković", Zagreb

Autor s matičnim brojem:
Mariastefania Antica, (113165)

Časopis indeksira:


  • Current Contents Connect (CCC)
  • Web of Science Core Collection (WoSCC)
    • Science Citation Index Expanded (SCI-EXP)
    • SCI-EXP, SSCI i/ili A&HCI
  • Scopus
  • MEDLINE