engleski

Respiratory symptoms and skin reactivity to dust mites in adult population of Zagreb region.

Respiratory symptoms and skin reactivity to Dermatophagoides pteronyssinus (DP), Lepidoglyphus destructor (LD) and Tyrophagus putrescentiae (TP) were studied in a random sample of 335 subjects, 163 men (37.5&#61617; 9.8 yrs ; smokers 110/163=67.5%) and 172 women (36.6&#61617; 8.8 yrs, smokers 106/172=61.6%). Upper airwyay symptoms (UAS) and lower airway symptoms (LAS) were collected by standardized questionnaire. Prick test (PT) with ALK_Epipharm allergens to DP, LD and TP was performed by standard method. An urtica D+d/2 3 mm and greater was considered a positive skin reaction (PT+). Significantly higher prevalence of PT+ was found in men than in women to DP (26.9%:12.2% ; P<0, 01), to LD (33.1%:19.2% ; P<0, 005) and not to TP (43.6%:34.3% ; n.s.). In DP PT+ men there were 32/44=72.7% LD PT+ subjects and 34/44=77.3% TP PT+ subjects. In DP PT+ women there was 11/21= 52.4% LD PT+ subjects and 10/21=47.6% TP PT+ subjects. Significantly higher mean skin reactivity was found in men than in women only to TP (5.13ą2.04:4.25ą1.13 ; P<0, 01). In PT+men there were 43/89=48.3% and in PT+ women 33/67=49.3% subjects with respiratory symptoms. In DP PT+ subjects there was higher prevalence of UAS than in LD and TP PT+ subjects (33.9%:18.7% ; P<0, 05). Our results show that although the prevalence of PT+ to LD and TP is much higher than to the DP, the connection to UAS is significantly better in DP PT+ subjects than in LD na TP PT+ subjects. This finding indicates that LD and TP PT+ reactions are less specific and need careful clinical interpretation.

Dust mites; storage mites; prick test; respiratory symptoms

nije evidentirano