engleski

Daily iodine intake in healthy children and adults in goitrous patients in non-endemic Yugoslav area

Daily iodine intake has been investigated in 52 healthy children (5-14 years), 112 healthy adults and in 39 patients with nontoxic goiter from the area of Zagreb/Yugoslavia. Fourteen goitrous patients received L-thyroxine 150 mcg daily at least three months before the examination. Iodine intake was estimated on the basis of urinary iodine eycretion (mcg I/g creatinine) in the first morning specimen. Iodine excretion in nontreated goitrous patients (92+/-30 ; mean+/-SD) was significantly lower than in healthy adults (112+/-38), while the value in treted goitrous patients (165+/-69) was significantly higher than that in nontreated goitrous and healthy adult subjects. The results suggest that Zagreb area, although classified as nonendemic, has borderline iodine intake, and that relative iodine deficiency is of importance of goiter formation. The authors plead for increased daily iodine intake though increased table salt iodisation from actual amount of 10 to 20 to 25 mg KI/kg salt in order to provide an average daily intake of 250 mcg of iodine.

Iodine intake ; nonendemic goiter ; Yugoslav area

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