Analyses of monoclonal antibodies reacting with porcine CD5: results from the Second International Swine CD Workshop (CROSBI ID 82376)
Prilog u časopisu | izvorni znanstveni rad | međunarodna recenzija
Podaci o odgovornosti
Pescovitz, M.D. ; Book, B.K. ; Aasted, B. ; Dominguez, J ; Bullido, R. ; Trebichavsky, I. ; Novikov, B. ; Valpotić, Ivica ; Tomašković, Marija ; Nielsen, J. ; Arn, S. ; Sachs, D.H. ; Lunney, J.K. ; Boyd, P.C. ; Walker, J. ; Lee R. ; Saalmüller, Armin
engleski
Analyses of monoclonal antibodies reacting with porcine CD5: results from the Second International Swine CD Workshop
Among the 57 monoclonal antibodies analyzed within the T-cell group, three mAb fell within cluster T13 including the CD5a standard b53b7 (No. 174). The two new mAb 1H6/8 (No. 058) and BB6-9G12 (No. 166) both precipitated 55 and 60 kDa proteins that were similar molecular weights as the standard. Staining patterns on the various cell types were similar. Both new antibodies inhibited the binding of the CD5a reference mAb b53b7 to peripheral lymphocytes. These mAbs, therefore both react with the CD5a epitope bringing the number of anti-porcine CD5 mAbs to eight, all of which appear to recognize the same epitope.
Monoclonal antibodies; CD5; T-cell; Porcine
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Podaci o izdanju
60 (3-4)
1998.
269-273
objavljeno
0165-2427
10.1016/S0165-2427(97)00103-7
