engleski

Pretransplant and Postransplant Predictor of Kidney Graft and Patientes Survival - a Single Center Aanalysis of 600 Cases (Croatia, Zagreb)

This retrospective study reviews risk and pitfalls for graft survival based on 32 years experience of single transplant center in Zagreb, Croatia. Four hundred and fifteen primary cadaveric kidneys (CD) transplant recipients and 102 living related (LR) recipients whose graft survived for more than six months were analyzed in the period 1982-2005. In LR transplantation, recipients of HLA haploidentical grafts had lower rejection risk and better graft survival, with half-estimate of 20 years 38%. CD first transplants matched graft had lower incidence of rejection and better survival (42% half-life) than haploidentical LR grafts. Expected half-life is 13, 6 years for LR and 16, 4 year's in-group of CD recipients. However in this analysis we shall consider different parameters that may contribute to graft and patient's survival. It will be analyzed: original disease, serum creatinine, relationship (graft type), rejection episodes, long term survival, recipient/donor age, gender, ischaemia time, and presensitization. The data were analyzed using Kaplan-Meier estimates. Good survival rate is depending on different immune and non-immune factors, which have stronger and more accurate impact in single center graft and patients survival.

kidney transplantation; Croatia

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