Napredna pretraga

Pregled bibliografske jedinice broj: 216513

Sugar Pucker Modulates the Cross-Correlated Relaxation Rates across the Glycosidic Bond in DNA


Sychrovsky, Vladimir; Mueller, Norbert; Schneider, Bohdan; Smrečki, Vilko; Špirko, Vladimir; Šponer, Jiri; Trantirek, Lukaš
Sugar Pucker Modulates the Cross-Correlated Relaxation Rates across the Glycosidic Bond in DNA // Journal of the American Chemical Society, 127 (2005), 42; 14663-14667 (međunarodna recenzija, članak, znanstveni)


Naslov
Sugar Pucker Modulates the Cross-Correlated Relaxation Rates across the Glycosidic Bond in DNA

Autori
Sychrovsky, Vladimir ; Mueller, Norbert ; Schneider, Bohdan ; Smrečki, Vilko ; Špirko, Vladimir ; Šponer, Jiri ; Trantirek, Lukaš

Izvornik
Journal of the American Chemical Society (0002-7863) 127 (2005), 42; 14663-14667

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
DNA; NMR; CSA; cross-correlated relaxation; glycosidic bond; sugar pucker

Sažetak
The dependence of N1/9 and C1' chemical shielding (CS) tensors on the glycosidic bond orientation (chi) and sugar pucker (P) in the DNA nucleosides 2'-deoxyadenosine, 2'-deoxyguanosine, 2'-deoxycytidine, and 2'-deoxythymidine was studied using the calculation methods of quantum chemistry. The results indicate that these CS-tensors exhibit a significant degree of conformational dependence on chi and P structural parameters. The presented data test underlying assumptions of currently established methods for interpretation of cross-correlated relaxation rates between the N1/9 chemical shielding tensor and C1'-H1' dipole-dipole (Ravindranathan et al. J. Biomol. NMR 2003, 27, 365-75. Duchardt et al. J. Am. Chem. Soc. 2004, 126, 1962-70) and highlight possible limitations of these methods when applied to DNA.

Izvorni jezik
Engleski

Znanstvena područja
Kemija



POVEZANOST RADA


Projekt / tema
0098059

Ustanove
Institut "Ruđer Bošković", Zagreb

Autor s matičnim brojem:
Vilko Smrečki, (190003)

Citiraj ovu publikaciju

Sychrovsky, Vladimir; Mueller, Norbert; Schneider, Bohdan; Smrečki, Vilko; Špirko, Vladimir; Šponer, Jiri; Trantirek, Lukaš
Sugar Pucker Modulates the Cross-Correlated Relaxation Rates across the Glycosidic Bond in DNA // Journal of the American Chemical Society, 127 (2005), 42; 14663-14667 (međunarodna recenzija, članak, znanstveni)
Sychrovsky, V., Mueller, N., Schneider, B., Smrečki, V., Špirko, V., Šponer, J. & Trantirek, L. (2005) Sugar Pucker Modulates the Cross-Correlated Relaxation Rates across the Glycosidic Bond in DNA. Journal of the American Chemical Society, 127 (42), 14663-14667.
@article{article, year = {2005}, pages = {14663-14667}, keywords = {DNA, NMR, CSA, cross-correlated relaxation, glycosidic bond, sugar pucker}, journal = {Journal of the American Chemical Society}, volume = {127}, number = {42}, issn = {0002-7863}, title = {Sugar Pucker Modulates the Cross-Correlated Relaxation Rates across the Glycosidic Bond in DNA}, keyword = {DNA, NMR, CSA, cross-correlated relaxation, glycosidic bond, sugar pucker} }

Časopis indeksira:


  • Current Contents Connect (CCC)
  • Web of Science Core Collection (WoSCC)
    • Science Citation Index Expanded (SCI-EXP)
    • SCI-EXP, SSCI i/ili A&HCI