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Pregled bibliografske jedinice broj: 215830

Liječenje kronične mijeloične leukemije u uznapredovaloj fazi bolesti imatinibom


Bulum, Josip; Labar, Boris; Mikulić, Mirta; Bogdanić, Vinko; Sertić, Dubravka; Nemet, Damir; Krečak-Gverić, V.; Kovačević, Jasminka; Serventi-Seiwerth, Ranka; Mrsić-Davidović, Sanja et al.
Liječenje kronične mijeloične leukemije u uznapredovaloj fazi bolesti imatinibom // Liječnički vjesnik : glasilo Hrvatskoga liječničkog zbora, 125 (2003), 176-9 (međunarodna recenzija, članak, znanstveni)


CROSBI ID: 215830 Za ispravke kontaktirajte CROSBI podršku putem web obrasca

Naslov
Liječenje kronične mijeloične leukemije u uznapredovaloj fazi bolesti imatinibom
(Treatment of chronic myeloid leukemia with imatinib in the accelerated stage of the disease)

Autori
Bulum, Josip ; Labar, Boris ; Mikulić, Mirta ; Bogdanić, Vinko ; Sertić, Dubravka ; Nemet, Damir ; Krečak-Gverić, V. ; Kovačević, Jasminka ; Serventi-Seiwerth, Ranka ; Mrsić-Davidović, Sanja ; Zadro, Renata ; Boban, Dubravka

Izvornik
Liječnički vjesnik : glasilo Hrvatskoga liječničkog zbora (0024-3554) 125 (2003); 176-9

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
kronična mijeloična leukemija; imatinib
(chronic myelogenous leukemia; imatinib)

Sažetak
Philadelphia chromosome positive chronic myeloid leukemia (Ph+ CML), in advanced stage of disease, is resistant to standard chemotherapy. Imatinib was found to be effective in these patients. This paper shows our preliminary results. Imatinib mesylate was given to 15 patients during a 9-month period. Nine of them were in accelerated phase and 6 in blastic crisis of Ph+ CML. Patients were evaluated for hematologic and cytogenetic responses. Imatinib mesylate induced complete haematologic response in 12 patients (80% and cytogenetic response in 8 patients (53%). Six patients (40%) had a major cytogenetic response. After a 9-month follow up Ph+ CML progressed in 9 patients (60%) and 4 of them died. The most frequent adverse effects were edema, nausea, neutropenia and thrombocytopenia. Imatinib mesylate has a substantial, but short term activity in the accelerated phase and blastic crisis of the Ph+ CML.

Izvorni jezik
Hrvatski, engleski

Znanstvena područja
Temeljne medicinske znanosti



POVEZANOST RADA


Projekti:
0214212

Ustanove:
Klinički bolnički centar Zagreb


Citiraj ovu publikaciju:

Bulum, Josip; Labar, Boris; Mikulić, Mirta; Bogdanić, Vinko; Sertić, Dubravka; Nemet, Damir; Krečak-Gverić, V.; Kovačević, Jasminka; Serventi-Seiwerth, Ranka; Mrsić-Davidović, Sanja et al.
Liječenje kronične mijeloične leukemije u uznapredovaloj fazi bolesti imatinibom // Liječnički vjesnik : glasilo Hrvatskoga liječničkog zbora, 125 (2003), 176-9 (međunarodna recenzija, članak, znanstveni)
Bulum, J., Labar, B., Mikulić, M., Bogdanić, V., Sertić, D., Nemet, D., Krečak-Gverić, V., Kovačević, J., Serventi-Seiwerth, R. & Mrsić-Davidović, S. (2003) Liječenje kronične mijeloične leukemije u uznapredovaloj fazi bolesti imatinibom. Liječnički vjesnik : glasilo Hrvatskoga liječničkog zbora, 125, 176-9.
@article{article, author = {Bulum, Josip and Labar, Boris and Mikuli\'{c}, Mirta and Bogdani\'{c}, Vinko and Serti\'{c}, Dubravka and Nemet, Damir and Kre\v{c}ak-Gveri\'{c}, V. and Kova\v{c}evi\'{c}, Jasminka and Serventi-Seiwerth, Ranka and Mrsi\'{c}-Davidovi\'{c}, Sanja and Zadro, Renata and Boban, Dubravka}, year = {2003}, pages = {176-9}, keywords = {kroni\v{c}na mijeloi\v{c}na leukemija, imatinib}, journal = {Lije\v{c}ni\v{c}ki vjesnik : glasilo Hrvatskoga lije\v{c}ni\v{c}kog zbora}, volume = {125}, issn = {0024-3554}, title = {Lije\v{c}enje kroni\v{c}ne mijeloi\v{c}ne leukemije u uznapredovaloj fazi bolesti imatinibom}, keyword = {kroni\v{c}na mijeloi\v{c}na leukemija, imatinib} }
@article{article, author = {Bulum, Josip and Labar, Boris and Mikuli\'{c}, Mirta and Bogdani\'{c}, Vinko and Serti\'{c}, Dubravka and Nemet, Damir and Kre\v{c}ak-Gveri\'{c}, V. and Kova\v{c}evi\'{c}, Jasminka and Serventi-Seiwerth, Ranka and Mrsi\'{c}-Davidovi\'{c}, Sanja and Zadro, Renata and Boban, Dubravka}, year = {2003}, pages = {176-9}, keywords = {chronic myelogenous leukemia, imatinib}, journal = {Lije\v{c}ni\v{c}ki vjesnik : glasilo Hrvatskoga lije\v{c}ni\v{c}kog zbora}, volume = {125}, issn = {0024-3554}, title = {Treatment of chronic myeloid leukemia with imatinib in the accelerated stage of the disease}, keyword = {chronic myelogenous leukemia, imatinib} }

Časopis indeksira:


  • Current Contents Connect (CCC)
  • Web of Science Core Collection (WoSCC)
    • SCI-EXP, SSCI i/ili A&HCI





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