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Pregled bibliografske jedinice broj: 215676

Botulinum toxin type A in rat model of muscle hyperalgesia


Bach-Rojecky, Lidija; Lacković, Zdravko; Relja, Maja
Botulinum toxin type A in rat model of muscle hyperalgesia // Abstracts of the 16th International Congress on Parkinson's Disease and Related Disorders ; u: Parkinsonism & related disorders 11 (2005) (S2) ; Poster symposia ; PS004 Botulinum toxin 105-106, 2005. str. 106-106 (poster, međunarodna recenzija, sažetak, znanstveni)


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Naslov
Botulinum toxin type A in rat model of muscle hyperalgesia

Autori
Bach-Rojecky, Lidija ; Lacković, Zdravko ; Relja, Maja

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, znanstveni

Izvornik
Abstracts of the 16th International Congress on Parkinson's Disease and Related Disorders ; u: Parkinsonism & related disorders 11 (2005) (S2) ; Poster symposia ; PS004 Botulinum toxin 105-106 / - , 2005, 106-106

Skup
International Congress on Parkinson's Disease and Related Disorders (16 ; 2005)

Mjesto i datum
,

Vrsta sudjelovanja
Poster

Vrsta recenzije
Međunarodna recenzija

Ključne riječi
botulinum toxin A; pain

Sažetak
Objective was to investigate the influence of botulinum toxin type A (BTX-A) on muscle hyperalgesia in rats induced with repeated intramuscular acidic saline injections. Right gastrocnemius muscle was injected twice with 100 l of pH 4 saline four days apart. Rat in one group received BTX-A ( 5 U/kg) into the plantar surface of the right hind-paws 5 days before injection, while the second group underweant the same treatment on the other side. After the second saline injection bilateral hypersensitivity (p<0.01) was observed. Pre-treatment with BTX-A prevented the development of hyperalgesia on both sides (p<0.01) only when toxin was injected into the ipsilateral hind-paws. When applied contralateraly the toxin inhibited the development of hypersensitivity on contralateral side only. These results demonstrate the effectivness of BTX-A in prevention of hyperalgesia induced by muscle injury.

Izvorni jezik
Engleski

Znanstvena područja
Temeljne medicinske znanosti

Napomena
Peter Franz Riederer, Susanne W. Burns, Manfred Gerlach (ur.) ; DOI: 10.1016/S1353-8020(05)80088-4 ; Riječ je o poster konferenciji na poziv, tj. o posteru i predavanju uz PP prezentaciju, odnosno o pozvanom predavanju.



POVEZANOST RADA


Projekti:
0108231
0108163

Ustanove:
Medicinski fakultet, Zagreb

Profili:

Avatar Url Zdravko Lacković (autor)

Avatar Url Lidija Bach-Rojecky (autor)

Avatar Url Maja Relja (autor)

Citiraj ovu publikaciju

Bach-Rojecky, Lidija; Lacković, Zdravko; Relja, Maja
Botulinum toxin type A in rat model of muscle hyperalgesia // Abstracts of the 16th International Congress on Parkinson's Disease and Related Disorders ; u: Parkinsonism & related disorders 11 (2005) (S2) ; Poster symposia ; PS004 Botulinum toxin 105-106, 2005. str. 106-106 (poster, međunarodna recenzija, sažetak, znanstveni)
Bach-Rojecky, L., Lacković, Z. & Relja, M. (2005) Botulinum toxin type A in rat model of muscle hyperalgesia. U: Abstracts of the 16th International Congress on Parkinson's Disease and Related Disorders ; u: Parkinsonism & related disorders 11 (2005) (S2) ; Poster symposia ; PS004 Botulinum toxin 105-106.
@article{article, year = {2005}, pages = {106-106}, keywords = {botulinum toxin A, pain}, title = {Botulinum toxin type A in rat model of muscle hyperalgesia}, keyword = {botulinum toxin A, pain} }
@article{article, year = {2005}, pages = {106-106}, keywords = {botulinum toxin A, pain}, title = {Botulinum toxin type A in rat model of muscle hyperalgesia}, keyword = {botulinum toxin A, pain} }

Časopis indeksira:


  • Current Contents Connect (CCC)
  • Web of Science Core Collection (WoSCC)
    • Science Citation Index Expanded (SCI-EXP)
    • SCI-EXP, SSCI i/ili A&HCI
  • Scopus
  • MEDLINE





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