Pretražite po imenu i prezimenu autora, mentora, urednika, prevoditelja

Napredna pretraga

Pregled bibliografske jedinice broj: 214190

Endosinusal treatment impact and prognostic value of IL-5 in chronic maxillary sinusitis


Baudoin, Tomislav; Drviš, Petar; Geber, Goran; Vagić, Davor; Kalogjera, Livije
Endosinusal treatment impact and prognostic value of IL-5 in chronic maxillary sinusitis // Annual Meeting of the American Academy of Otolaryngology - Head and Neck Surgery / Harner, Stephen G. (ur.).
Rochester: Mosby, 2004. str. 54-54 (predavanje, međunarodna recenzija, sažetak, znanstveni)


CROSBI ID: 214190 Za ispravke kontaktirajte CROSBI podršku putem web obrasca

Naslov
Endosinusal treatment impact and prognostic value of IL-5 in chronic maxillary sinusitis

Autori
Baudoin, Tomislav ; Drviš, Petar ; Geber, Goran ; Vagić, Davor ; Kalogjera, Livije

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, znanstveni

Izvornik
Annual Meeting of the American Academy of Otolaryngology - Head and Neck Surgery / Harner, Stephen G. - Rochester : Mosby, 2004, 54-54

Skup
Annual Meeting of the American Academy of Otolaryngology - Head and Neck Surgery

Mjesto i datum
Los Angeles, SAD, 19.-22.09.2004

Vrsta sudjelovanja
Predavanje

Vrsta recenzije
Međunarodna recenzija

Ključne riječi
Chronic sinusitis ; symptom ; treatment
(Chronic sinusitis ; symptom ; treatment ; prognosis)

Sažetak
The aim of the study was to evaluate subjective outcomes in patients with chronic maxillary sinusitis after steroid/antibiotic endosinusal treatment. Furthermore, the aim was to test the hypothesis that pretreatment levels of interleukin-5 in sinus fluid could predict response to endosinusal steroid/antibiotic treatment. Thirty patients with chronic maxillary sinusitis were recruited for the study. Patients were treated endosinusally with 2 mg dexamethasone and 40 mg gentamycine per maxillary sinus for 5 days. Patients rated nasal/CRS disease-specific symptoms and completed a self-administered questionnaire concerning sinusitis symptoms at inclusion and after 30 days. Sinus lavage, collected at inclusion, was analyzed for IL-5 concentration. 56.6% of patients had improvement after endonasal treatment with decrease in symptoms (responders), and 43.4% were unchanged or worsened after treatment (nonresponders). Significant improvement was noted for overall sinusitis symptoms score (P=0.02)and for obstruction, postnasal drip, headache, sneezing, and cough (P<0.05). There is positive correlation between baseline IL-5 level in sinus lavage and improvement rate of overall sinusitis symptoms score (P<0.01) and improvement rate of nasal secretion score (P<0.01). Steroid-antibiotic endosinusal treatment in patients with chronic maxillary sinusitis was proven effective in reducing subjective sinusitis symptoms. Improvement rate to endosinusal treatment is expected to be higher in patients with increased level of IL-5 in maxillary sinus lavage. Increased concentrations of IL-5 in sinus fluid might be used as predictor of a good response to endosinusal treatment of maxillary chronic sinusitis.

Izvorni jezik
Engleski



POVEZANOST RADA


Projekti:
0108022
0065001

Ustanove:
Stomatološki fakultet, Zagreb,
Medicinski fakultet, Zagreb,
KBC "Sestre Milosrdnice"

Profili:

Avatar Url Tomislav Baudoin (autor)

Avatar Url Livije Kalogjera (autor)

Avatar Url Davor Vagić (autor)

Avatar Url Petar Drviš (autor)

Avatar Url Goran Geber (autor)


Citiraj ovu publikaciju:

Baudoin, Tomislav; Drviš, Petar; Geber, Goran; Vagić, Davor; Kalogjera, Livije
Endosinusal treatment impact and prognostic value of IL-5 in chronic maxillary sinusitis // Annual Meeting of the American Academy of Otolaryngology - Head and Neck Surgery / Harner, Stephen G. (ur.).
Rochester: Mosby, 2004. str. 54-54 (predavanje, međunarodna recenzija, sažetak, znanstveni)
Baudoin, T., Drviš, P., Geber, G., Vagić, D. & Kalogjera, L. (2004) Endosinusal treatment impact and prognostic value of IL-5 in chronic maxillary sinusitis. U: Harner, S. (ur.)Annual Meeting of the American Academy of Otolaryngology - Head and Neck Surgery.
@article{article, editor = {Harner, S.}, year = {2004}, pages = {54-54}, keywords = {Chronic sinusitis, symptom, treatment}, title = {Endosinusal treatment impact and prognostic value of IL-5 in chronic maxillary sinusitis}, keyword = {Chronic sinusitis, symptom, treatment}, publisher = {Mosby}, publisherplace = {Los Angeles, SAD} }
@article{article, editor = {Harner, S.}, year = {2004}, pages = {54-54}, keywords = {Chronic sinusitis, symptom, treatment, prognosis}, title = {Endosinusal treatment impact and prognostic value of IL-5 in chronic maxillary sinusitis}, keyword = {Chronic sinusitis, symptom, treatment, prognosis}, publisher = {Mosby}, publisherplace = {Los Angeles, SAD} }




Contrast
Increase Font
Decrease Font
Dyslexic Font