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Pregled bibliografske jedinice broj: 213048

Uloga farmakogenetičkih varijacija u terapiji depresije


Božina, Nada
Uloga farmakogenetičkih varijacija u terapiji depresije, 2005., doktorska disertacija, Medicinski fakultet, Zagreb


CROSBI ID: 213048 Za ispravke kontaktirajte CROSBI podršku putem web obrasca

Naslov
Uloga farmakogenetičkih varijacija u terapiji depresije
(The role of pharmacogenetic variations in the therapy of depression)

Autori
Božina, Nada

Vrsta, podvrsta i kategorija rada
Ocjenski radovi, doktorska disertacija

Fakultet
Medicinski fakultet

Mjesto
Zagreb

Datum
11.10

Godina
2005

Stranica
116

Mentor
Stavljenić Rukavina, Ana

Ključne riječi
farmakogenetičke varijacije; depresija;
(pharmacogenetic variations; depression)

Sažetak
Genetic variations of metabolic enzymes and transporter proteins are important determinants of pharmacotherapy efficacy and toxicity. In addition, interindividual, interethnic differences in the prevalence of genetic variations are signifficanz. In this study, pharmacogenetic analysis was performed in Croatian healthy population and patients with depression. The influence of genetic variations of metabolic enzymes: CYP2C9, CYP2C19, CYP2D6, CYP3A4 and transporter proteins: P-glycoprotein (MDR1) and serotonin transporter (SERT) on pharmacologic and toxicologic effects of major depression therapy were investigated. The study included 286 healthy subjects and 114 patients with major depression.

Izvorni jezik
Hrvatski



POVEZANOST RADA


Projekti:
0108247

Ustanove:
Medicinski fakultet, Zagreb


Citiraj ovu publikaciju

Božina, Nada
Uloga farmakogenetičkih varijacija u terapiji depresije, 2005., doktorska disertacija, Medicinski fakultet, Zagreb
Božina, N. (2005) 'Uloga farmakogenetičkih varijacija u terapiji depresije', doktorska disertacija, Medicinski fakultet, Zagreb.
@phdthesis{phdthesis, author = {Bo\v{z}ina, N.}, year = {2005}, pages = {116}, keywords = {farmakogeneti\v{c}ke varijacije, depresija, }, title = {Uloga farmakogeneti\v{c}kih varijacija u terapiji depresije}, keyword = {farmakogeneti\v{c}ke varijacije, depresija, }, publisherplace = {Zagreb} }
@phdthesis{phdthesis, author = {Bo\v{z}ina, N.}, year = {2005}, pages = {116}, keywords = {pharmacogenetic variations, depression}, title = {The role of pharmacogenetic variations in the therapy of depression}, keyword = {pharmacogenetic variations, depression}, publisherplace = {Zagreb} }




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