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Pregled bibliografske jedinice broj: 209129

Radioiodine uptake in thyroid cancer patients after diagnostic application of low i-131 dose


Huić, Dražen; Medvedec, Mario; Dodig, Damir; Popović, Slavko; Ivančević, Darko; Pavlinović, Željka; Žuvić, Marijan
Radioiodine uptake in thyroid cancer patients after diagnostic application of low i-131 dose // Nuclear medicine communications, 17 (1996), 10; 839-842 (međunarodna recenzija, članak, znanstveni)


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Naslov
Radioiodine uptake in thyroid cancer patients after diagnostic application of low i-131 dose

Autori
Huić, Dražen ; Medvedec, Mario ; Dodig, Damir ; Popović, Slavko ; Ivančević, Darko ; Pavlinović, Željka ; Žuvić, Marijan

Izvornik
Nuclear medicine communications (0143-3636) 17 (1996), 10; 839-842

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
thyroid cancer; radioiodine therapy; in vivo dosimetry

Sažetak
The aim of our study was to investigate the influence of diagnostic administration of 74 MBq of I-131 on subsequent uptake of therapeutic radioiodine in thyroid cancer patients. The retention measurements were performed by whole body counter in 24 patients 6 weeks after total thyreoidectomy. Profile scans were performed 2, 24, 48 and 72 hours after administration of the diagnostic activity and 72 hours after administration of the ablation-therapeutic activity (4.4 GBq). The mean effective half-life of the diagnostic activity in thyroid remnants was 40.3 ± ; ; 23.0 hours (range 15.5 - 88.8). The radioiodine uptake in thyroid remnants obtained with the subsequent ablation activity 72 hours after administration was in average only 30.4% ± ; ; 19.8% (range 6.8% - 73.4%) of those predicted by the diagnostic study. The more pronounced uptake reduction was connected with longer effective half-life of iodine and higher 24-hours uptake in thyroid remnants, with longer time interval between surgery and administration of the diagnostic activity and shorter period between administration of the diagnostic and ablation activity. Our results showed that diagnostic activity of 74 MBq of I-131 markedly reduced thyroid uptake during ablation procedure, what should be taken into account in a radiation dose planning, whenever a quantitative dosimetric study is used.

Izvorni jezik
Engleski



POVEZANOST RADA


Projekti:
214008

Ustanove:
Klinički bolnički centar Zagreb


Citiraj ovu publikaciju:

Huić, Dražen; Medvedec, Mario; Dodig, Damir; Popović, Slavko; Ivančević, Darko; Pavlinović, Željka; Žuvić, Marijan
Radioiodine uptake in thyroid cancer patients after diagnostic application of low i-131 dose // Nuclear medicine communications, 17 (1996), 10; 839-842 (međunarodna recenzija, članak, znanstveni)
Huić, D., Medvedec, M., Dodig, D., Popović, S., Ivančević, D., Pavlinović, Ž. & Žuvić, M. (1996) Radioiodine uptake in thyroid cancer patients after diagnostic application of low i-131 dose. Nuclear medicine communications, 17 (10), 839-842.
@article{article, year = {1996}, pages = {839-842}, keywords = {thyroid cancer, radioiodine therapy, in vivo dosimetry}, journal = {Nuclear medicine communications}, volume = {17}, number = {10}, issn = {0143-3636}, title = {Radioiodine uptake in thyroid cancer patients after diagnostic application of low i-131 dose}, keyword = {thyroid cancer, radioiodine therapy, in vivo dosimetry} }
@article{article, year = {1996}, pages = {839-842}, keywords = {thyroid cancer, radioiodine therapy, in vivo dosimetry}, journal = {Nuclear medicine communications}, volume = {17}, number = {10}, issn = {0143-3636}, title = {Radioiodine uptake in thyroid cancer patients after diagnostic application of low i-131 dose}, keyword = {thyroid cancer, radioiodine therapy, in vivo dosimetry} }

Časopis indeksira:


  • Current Contents Connect (CCC)
  • Web of Science Core Collection (WoSCC)
    • SCI-EXP, SSCI i/ili A&HCI
  • Scopus
  • MEDLINE


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