Intricate patterns of sequence divergence and conservation in an organizationally complex Donax trunculus satellite DNA family (CROSBI ID 509030)
Prilog sa skupa u zborniku | sažetak izlaganja sa skupa
Podaci o odgovornosti
Petrović, Vlatka ; Plohl, Miroslav
engleski
Intricate patterns of sequence divergence and conservation in an organizationally complex Donax trunculus satellite DNA family
Characterization of a novel satellite DNA family from the bivalve mollusc Donax trunculus revealed extensive grouping of monomer sequence variants and formation of subfamilies identified by distinctive combinations of diagnostic nucleotides. In addition to the tandemly organized 169 bp long monomers, at least one subfamily was created through amplification of two adjacent repeats in a higher order register, while sequence rearrangements led to the creation of a complex satellite unit. Irrespective of the differences that exist between the constituent subunits, higher order repeats can also be further divided into variant subgroups. The localization pattern of diagnostic changes indicates that sequence homogenization mechanisms are not only effective in the spread of the higher order repeat as a whole, but also act on a lower scale. Nucleotide diversity analysis of all variants of the entire satellite family revealed the persistence of conserved sequence segments which stands in contrast to the sequence and organizational divergence of various groups, and may indicate functional constraints on the evolution of this satellite.
bivalve molluscs; nucleotide diversity; homogenization; satellite subfamily
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Podaci o prilogu
31-x.
2005.
objavljeno
Podaci o matičnoj publikaciji
Embo workshop 2005 - Chromosome structural elements: from DNA sequence to function
Ascenzioni, Fiorentina
Rim: Casa Editrice Universita degli Studi di Roma "La Sapienza"
Podaci o skupu
Embo Workshop 2005 - Chromosome structural elements : from DNA sequence to function
poster
29.09.2005-03.10.2005
Rim, Italija