engleski

Salivary interleukin 6 and tumor necrosis factor alpha in patients with burning mouth syndrome.

Burning mouth syndrome (BMS) is characterized by burning symptoms on the clinically healthy oral mucosa. So far, etiology of BMS is still unknown. We hypothesized that maybe inflammation which is not clinically apparent might lead to burning symptoms which would then result in altered cytokine profile. In the 28 female patients with burning mouth syndrome (age range 48-80, mean 64.05 years) and 28 female controls (age range 40-75, mean 63.82) by use of ELISA, interleukin 6 (IL-6) and tumor necrosis factor &#8211; &#945; (TNF-&#945; ) levels were determined. Statistical analysis included use of independent sample t test and values lower than 0.05 (p<0.05) were considered as significant. Our results show that no significant differences between patients and controls regarding salivary IL-6 and TNF-&#945; could be found.

interleukin 6; tumor necrosis factor alpha; burning mouth syndrome; saliva

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