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Pregled bibliografske jedinice broj: 202777

Effectiveness of latanoprost (Xalatan TM) monotherapy in newly discovered and previously medicamentously treated primary open angle glaucoma patients


Pavan, Josip; Štambuk, Nikola; Ćurković, Tihomir; Konjevoda, Paško; Pavan-Jukić, Doroteja; Gotovac, Marta; Karaman, Ksenija
Effectiveness of latanoprost (Xalatan TM) monotherapy in newly discovered and previously medicamentously treated primary open angle glaucoma patients // Collegium antropologicum, 29 (2005), 1; 315-319 (međunarodna recenzija, članak, znanstveni)


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Naslov
Effectiveness of latanoprost (Xalatan TM) monotherapy in newly discovered and previously medicamentously treated primary open angle glaucoma patients

Autori
Pavan, Josip ; Štambuk, Nikola ; Ćurković, Tihomir ; Konjevoda, Paško ; Pavan-Jukić, Doroteja ; Gotovac, Marta ; Karaman, Ksenija

Izvornik
Collegium antropologicum (0350-6134) 29 (2005), 1; 315-319

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
latanoprost ; Xalatan TM ; monotherapy ; glaucoma ; treatment ; effectiveness

Sažetak
The effectiveness of latanoprost (Xalatan TM) monotherapy in primary open angle glaucoma (POAG) was evaluated. Latanoprost is a prostaglandin analogue, the pure 15(R) epimer of 13, 14 dihydro 17 phenyl 18, 19, 20 trinor PGF2alpha isopropyl ester. As a prodrug it is being activated by enzymatic hydrolysis in the cornea after which it becomes active acid of latanoprost. Latanoprost is lowering the intraocular pressure (IOP) by increasing the uveoscleral outflow. In this study, latanoprost was used once daily as monotherapy what offers much better compliance for the patients than other combinations of drugs, preserving good IOP control. Based on the significant reduction of the IOp, measured on the day 60 ofthe trial (mean change in IOP was -5.1 mmHg, with 95% confidence interval in range from -5.6 to -4.5), it is concluded that use of latanoprost is advisable when calculating better IOP control, few side-effects and reductions in costs of potential surgical procedures.

Izvorni jezik
Engleski

Znanstvena područja
Kemija, Temeljne medicinske znanosti, Kliničke medicinske znanosti



POVEZANOST RADA


Projekti:
0098097
0098059

Ustanove:
Institut "Ruđer Bošković", Zagreb

Citiraj ovu publikaciju

Pavan, Josip; Štambuk, Nikola; Ćurković, Tihomir; Konjevoda, Paško; Pavan-Jukić, Doroteja; Gotovac, Marta; Karaman, Ksenija
Effectiveness of latanoprost (Xalatan TM) monotherapy in newly discovered and previously medicamentously treated primary open angle glaucoma patients // Collegium antropologicum, 29 (2005), 1; 315-319 (međunarodna recenzija, članak, znanstveni)
Pavan, J., Štambuk, N., Ćurković, T., Konjevoda, P., Pavan-Jukić, D., Gotovac, M. & Karaman, K. (2005) Effectiveness of latanoprost (Xalatan TM) monotherapy in newly discovered and previously medicamentously treated primary open angle glaucoma patients. Collegium antropologicum, 29 (1), 315-319.
@article{article, year = {2005}, pages = {315-319}, keywords = {latanoprost, Xalatan TM, monotherapy, glaucoma, treatment, effectiveness}, journal = {Collegium antropologicum}, volume = {29}, number = {1}, issn = {0350-6134}, title = {Effectiveness of latanoprost (Xalatan TM) monotherapy in newly discovered and previously medicamentously treated primary open angle glaucoma patients}, keyword = {latanoprost, Xalatan TM, monotherapy, glaucoma, treatment, effectiveness} }
@article{article, year = {2005}, pages = {315-319}, keywords = {latanoprost, Xalatan TM, monotherapy, glaucoma, treatment, effectiveness}, journal = {Collegium antropologicum}, volume = {29}, number = {1}, issn = {0350-6134}, title = {Effectiveness of latanoprost (Xalatan TM) monotherapy in newly discovered and previously medicamentously treated primary open angle glaucoma patients}, keyword = {latanoprost, Xalatan TM, monotherapy, glaucoma, treatment, effectiveness} }

Časopis indeksira:


  • Current Contents Connect (CCC)
  • Web of Science Core Collection (WoSCC)
    • Social Science Citation Index (SSCI)
    • SCI-EXP, SSCI i/ili A&HCI
  • Scopus
  • MEDLINE


Uključenost u ostale bibliografske baze podataka:


  • Sociological Abstracts
  • Index Medicus
  • Abstracts in Anthroplogy
  • CIRS





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