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Pregled bibliografske jedinice broj: 197038

6-amino-6-deoxyascorbic acid induces apoptosis in human tumor cells


Grdiša, Mirica; Kralj, Marijeta; Eckert-Maksić, Mirjana; Maksić, Zvonimir
6-amino-6-deoxyascorbic acid induces apoptosis in human tumor cells // Journal of cancer research and clinical oncology, 121 (1995), 2; 98-102 doi:10.1007/BF01202220 (međunarodna recenzija, članak, znanstveni)


Naslov
6-amino-6-deoxyascorbic acid induces apoptosis in human tumor cells

Autori
Grdiša, Mirica ; Kralj, Marijeta ; Eckert-Maksić, Mirjana ; Maksić, Zvonimir

Izvornik
Journal of cancer research and clinical oncology (0171-5216) 121 (1995), 2; 98-102

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
6-amino-6-deoxyascorbic acid ; apoptosis

Sažetak
6-Amino-6-deoxyascorbic acid was found to inhibit human tumor cell growth. The antitumor effect depends on the tumor type and concentration of the acid. After cell treatment with 6-amino-6-deoxyascorbic acid, drastic morphological changes were found. Although image analysis did not show a difference in p53 and c-myc gene expression, the appearance of chromatin aggregation and DNA fragmentation points to apoptosis or programmed cell death.

Izvorni jezik
Engleski

Znanstvena područja
Temeljne medicinske znanosti



POVEZANOST RADA


Ustanove
Institut "Ruđer Bošković", Zagreb

Časopis indeksira:


  • Current Contents Connect (CCC)
  • Web of Science Core Collection (WoSCC)
    • Science Citation Index Expanded (SCI-EXP)
    • SCI-EXP, SSCI i/ili A&HCI
  • Scopus
  • MEDLINE


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