Napredna pretraga

Pregled bibliografske jedinice broj: 196104

Derivatives of 1-thiadibenzoazulenes and their biological activity


Merćep, Mladen; Mesić, Milan; Benko, Iva; Pešić, Dijana;
Derivatives of 1-thiadibenzoazulenes and their biological activity
(2003)


Naslov
Derivatives of 1-thiadibenzoazulenes and their biological activity

Autori
Merćep, Mladen ; Mesić, Milan ; Benko, Iva ; Pešić, Dijana ;

Godina
2003

Nositelj prava
PLIVA-Research Institute, Zagreb, Hrvatska

Sažetak
The present invention relates to (a) novel 1-thiadibenzoazulene derivatives of the formula (I), (b) to their pharmacologically acceptable esters, salts and solvates, (c) to process and intermediates for the preparation thereof, (d) to a process for preparing pharmaceutical formulations for the treatment of inflammatory diseases and conditions in humans and animals. These compounds inhibit the tumor necrosis factor-alpha (TNF-alpha) production and interleukin-1 (IL-1) production and exibit an analgetic action.

Izvorni jezik
Engleski

Znanstvena područja
Kemija, Farmacija



POVEZANOST RADA


Ustanove
Pliva-Istraživački institut

Autor s matičnim brojem:
Milan Mesić, (159405)