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Pregled bibliografske jedinice broj: 195981

Use of 11H-dibenzo[b, f]oxepin-10-one and 11H-dibenzo[b, f]thiepin-10-one as core units for the synthesis of various dibenzo[e, h]azulenes


Mesić, Milan; Pešić, Dijana; Ozimec Landek, Ivana; Džapo, Iva; Modrić, Marina; Rupčić, Renata; Trojko, Rudolf; Merćep, Mladen
Use of 11H-dibenzo[b, f]oxepin-10-one and 11H-dibenzo[b, f]thiepin-10-one as core units for the synthesis of various dibenzo[e, h]azulenes // XXIst European Colloquium on Heterocyclic Chemistry
Sopron, Mađarska, 2004. (poster, nije recenziran, neobjavljeni rad, znanstveni)


Naslov
Use of 11H-dibenzo[b, f]oxepin-10-one and 11H-dibenzo[b, f]thiepin-10-one as core units for the synthesis of various dibenzo[e, h]azulenes

Autori
Mesić, Milan ; Pešić, Dijana ; Ozimec Landek, Ivana ; Džapo, Iva ; Modrić, Marina ; Rupčić, Renata ; Trojko, Rudolf ; Merćep, Mladen

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, neobjavljeni rad, znanstveni

Skup
XXIst European Colloquium on Heterocyclic Chemistry

Mjesto i datum
Sopron, Mađarska, 12-15.09.2004

Vrsta sudjelovanja
Poster

Vrsta recenzije
Nije recenziran

Ključne riječi
Dibenzo[e; h]azulenes; synthesis; 11H-dibenzo[b; f]oxepin-10-one; 11H-dibenzo[b; f]thiepin-10-one

Sažetak
The tricyclic structure of dibenzo[b, f]oxepines and dibenzo[b, f]thiepines was identified as an interesting scaffold which numerous derivatives show different pharmacological activities (antipsychotic, sedative, antidepressant, analgesic, antihypertensive, nonsteroidal anti-inflammatory, tromboxane antagonism). This broad biological activity prompted use of dibenzo[b, f]oxepines and dibenzo[b, f]thiepines as intermediates for the synthesis of various polycyclic compounds. Herein we wish to report some efficient syntheses of a few tetracyclic dibenzo[e, h]azulenes starting from 11H-dibenzo[b, f]oxepin-10-one and its sulphur analogue (1). According to target molecules requested, those tetracyclic compounds can be further transformed by different functional group interconversions.

Izvorni jezik
Engleski

Znanstvena područja
Kemija



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