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izvor podataka: crosbi

Sequence divergence and conservation in organizationally distinct subfamilies of Donax trunculus satellite DNA (CROSBI ID 113854)

Prilog u časopisu | izvorni znanstveni rad | međunarodna recenzija

Petrović, Vlatka ; Plohl, Miroslav Sequence divergence and conservation in organizationally distinct subfamilies of Donax trunculus satellite DNA // Gene, 362 (2005), 37-43. doi: 10.1016/j.gene.2005.06.044

Podaci o odgovornosti

Petrović, Vlatka ; Plohl, Miroslav

engleski

Sequence divergence and conservation in organizationally distinct subfamilies of Donax trunculus satellite DNA

Characterization of a low-copy number DTF1 satellite DNA detected in the bivalve mollusc Donax trunculus revealed extensive grouping of monomer sequence variants into subfamilies identified by distinctive combinations of diagnostic nucleotides. It can be anticipated that a large number of subfamilies exists in the genome. In addition to the tandem organization of 169 bp long monomers, at least one subfamily was created through amplification of adjacent repeats in a higher order register. This complex satellite unit consists of two distinctive monomer variants that differ both in specific nucleotide changes and in a deleted segment partially substituted with a short unrelated sequence element. Most of the nucleotide substitutions differing between subfamilies are highly homogenized within a corresponding group of monomer variants, and intra-subfamily variability in general is low. Nucleotide diversity analysis of all sequenced variants of DTF1 satellite revealed the presence of two conserved segments, while the rest of the monomer sequence shows uniform and considerably higher level of variability. The persistence of conserved segments stands in contrast to the sequence and organizational divergence of monomer variant groups, and may indicate constraints in the evolution of DTF1 satellite repeats.

tandem repeats ; higher order repeats ; concerted evolution ; conserved domains ; bivalve molluscs

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Podaci o izdanju

362

2005.

37-43

objavljeno

0378-1119

10.1016/j.gene.2005.06.044

Povezanost rada

Biologija

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