The Synthesis of Aza[N]ladderanes and Azahomo[N]ladderanes Containing Beta-lactams at the terminus (CROSBI ID 77593)
Prilog u časopisu | izvorni znanstveni rad | međunarodna recenzija
Podaci o odgovornosti
Warrener R.N. ; Russell, R.A. ; Margetić, Davor
engleski
The Synthesis of Aza[N]ladderanes and Azahomo[N]ladderanes Containing Beta-lactams at the terminus
5-Azabicyclo[2.2.0]hex-2-en-6-one 1 undergoes [2 pi+2 pi] cycloaddition with dimethyl acetylene dicarboxylate (Ru-catalysed) to yield aza[3]ladderane 2 which is transformed to aza[5]ladderanes 4 and 5 on treatment with cyclobutadiene and to azahomo[5]ladderanes 10 and 11 on reaction with cyclopentadiene. The specificities of these cycloaddition reactions are in agreement with predictions made using ab initio calculations. Chlorosulfonyl iso cyan ate addition is used to access azahomo[4]ladderane 14.
Cycloaddition-specificities; Polycyclobutanes; Chlorosulfonyl isocyanate. Ab initio calculations
nije evidentirano
nije evidentirano
nije evidentirano
nije evidentirano
nije evidentirano
nije evidentirano