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Pregled bibliografske jedinice broj: 188003

Osteosarcoma and Ewing's sarcoma in children and adolescents: retrospective clinicopathological study


Ilić, Ivana; Manojlović, Spomenka; Ćepulić, Mladen; Orlić, Dubravko; Seiwerth, Sven
Osteosarcoma and Ewing's sarcoma in children and adolescents: retrospective clinicopathological study // Croatian medical journal, 45 (2004), 6; 740-745 (međunarodna recenzija, članak, znanstveni)


CROSBI ID: 188003 Za ispravke kontaktirajte CROSBI podršku putem web obrasca

Naslov
Osteosarcoma and Ewing's sarcoma in children and adolescents: retrospective clinicopathological study

Autori
Ilić, Ivana ; Manojlović, Spomenka ; Ćepulić, Mladen ; Orlić, Dubravko ; Seiwerth, Sven

Izvornik
Croatian medical journal (0353-9504) 45 (2004), 6; 740-745

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
adolescent; bone neoplasms; child; osteosarcoma; sarcoma; Ewing's

Sažetak
AIM: Almost 20 different prognostic factors have so far been investigated in childhood bone tumors, but apart from clinical stage the results have been inconclusive. We evaluated possible prognostic factors of malignant bone tumors in children and adolescents. METHODS: Seventy children and adolescents, who have been treated for bone sarcomas (36 with osteosarcoma and 34 with Ewing's sarcoma) at the Children's Hospital in Zagreb and the Orthopedic Clinic of the Zagreb University School of Medicine were included in the study. We analyzed 9 variables: clinical stage, patient age and sex, tumor size and location, location of metastases, chemotherapy response, concentration of lactate dehydrogenase (LDH) and erythrocyte sedimentation rate (ESR), and chondroid differentiation in osteosarcoma. RESULTS: The clinical stage was the most important prognostic factor for both type of tumors. Lactate dehydrogenase in patients with Ewing's sarcoma (p=0.033) and in patients with osteosarcoma (p=0.015) as well as erythrocyte sedimentation rate (p<0.001 and p=0.014, respectively) may also be of predictive value. CONCLUSION: Elevated erythrocyte sedimentation rate and high LDH concentration seem to be of importance in both Ewing's sarcoma and osteosarcoma, regardless of their different pathogenesis or pathohistology.

Izvorni jezik
Engleski

Znanstvena područja
Temeljne medicinske znanosti



POVEZANOST RADA


Projekti:
0108238

Ustanove:
Medicinski fakultet, Zagreb


Citiraj ovu publikaciju

Ilić, Ivana; Manojlović, Spomenka; Ćepulić, Mladen; Orlić, Dubravko; Seiwerth, Sven
Osteosarcoma and Ewing's sarcoma in children and adolescents: retrospective clinicopathological study // Croatian medical journal, 45 (2004), 6; 740-745 (međunarodna recenzija, članak, znanstveni)
Ilić, I., Manojlović, S., Ćepulić, M., Orlić, D. & Seiwerth, S. (2004) Osteosarcoma and Ewing's sarcoma in children and adolescents: retrospective clinicopathological study. Croatian medical journal, 45 (6), 740-745.
@article{article, year = {2004}, pages = {740-745}, keywords = {adolescent, bone neoplasms, child, osteosarcoma, sarcoma, Ewing's}, journal = {Croatian medical journal}, volume = {45}, number = {6}, issn = {0353-9504}, title = {Osteosarcoma and Ewing's sarcoma in children and adolescents: retrospective clinicopathological study}, keyword = {adolescent, bone neoplasms, child, osteosarcoma, sarcoma, Ewing's} }
@article{article, year = {2004}, pages = {740-745}, keywords = {adolescent, bone neoplasms, child, osteosarcoma, sarcoma, Ewing's}, journal = {Croatian medical journal}, volume = {45}, number = {6}, issn = {0353-9504}, title = {Osteosarcoma and Ewing's sarcoma in children and adolescents: retrospective clinicopathological study}, keyword = {adolescent, bone neoplasms, child, osteosarcoma, sarcoma, Ewing's} }

Časopis indeksira:


  • Current Contents Connect (CCC)
  • Web of Science Core Collection (WoSCC)
    • Science Citation Index Expanded (SCI-EXP)
    • SCI-EXP, SSCI i/ili A&HCI
  • Scopus
  • MEDLINE





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