Lymphocyte subpopulations in the blood and cerebrospinal fluid of multiple sclerosis patients in active disease (CROSBI ID 111671)
Prilog u časopisu | izvorni znanstveni rad | međunarodna recenzija
Podaci o odgovornosti
Rukavina, Daniel ; Sepčić, Juraj ; Dorić, Miljenko ; Ledić, Petar ; Zaputović, Luka ; Eberhardt, Predrag
engleski
Lymphocyte subpopulations in the blood and cerebrospinal fluid of multiple sclerosis patients in active disease
Lymphocyte subpopulations (total T cells, active T cells and B cells) were simultaneously analyzed in peripheral blood and CSF of MS patients. All patients were in active disease, 3 to 4 weeks after first signs of disease activation appeared. Per cent levels and absolute numbers of examined lymphocyte subpopulations in the blood of MS patients were significantly lower than in healthy controls. In MS, the level of active T lymphocytes was lower in CSF than in peripheral blood. The results support our earlier observations relating to the role of active T lymphocytes in the clinical course of disease.
T cells ; B cells ; blood ; cerebrospinal fluid ; multiple sclerosis
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Podaci o izdanju
Povezanost rada
Kliničke medicinske znanosti