THYROID DYSFUNCTION AND BONE MINERAL DENSITY IN THE EARLY POSTMENOPAUSE (CROSBI ID 504638)
Prilog sa skupa u zborniku | sažetak izlaganja sa skupa | međunarodna recenzija
Podaci o odgovornosti
Jelčić, Jozo ; Kušec, Vesna ; Kifer, Tomislav Delija, Alboran ; Koršić, Mirko
engleski
THYROID DYSFUNCTION AND BONE MINERAL DENSITY IN THE EARLY POSTMENOPAUSE
Background: The most common form of primary osteoporosis occurrs in the postmenopause with most of the bone mass lost in the early postmenopause. Hyperthyroidism is one of the major risk factors for secondary osteoporosis, due to increased bone turnover and accelerated bone loss. Objectives: The aim of this study was to investigate bone density in postmenopausal women with thyroid dysfunction. Methods: This retrospective analysis comprised 42 hyperthyroid, 92 hypothyroid and 562 euthyroid patients aged 40-85 years. Bone mineral density (BMD) was measured at the lumbar spine and femoral neck by dual X-ray absorptiometry. Results: Patients with hypothyroidism were significantly younger than those without thyroid disorder (59.7 yr. vs. 62.1 yr.) and had significantly higher BMD in the lumbar spine and hip. Analysis of data for age groups revealed that the statistically significant difference (p<0.005) for the lumbar spine and hip BMD was found only for the 51-55 year old patients. No difference existed between the other two pairs of patient groups, i.e. the euthyroid and hyperthyroid and the hypothyroid and the hyperthyroid. There was no difference in incidence of osteopenia (T-score <-1) and osteoporosis (T-score <-2.5) between the three patient groups. Conclusion: These results suggest a protective effect of hypothyroidism on the skeleton in the early postmenopause probably by decelerated bone turnover and bone loss.
bone density in postmenopausal women; thyroid dysfunction
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Podaci o prilogu
2004.
objavljeno
Podaci o matičnoj publikaciji
Podaci o skupu
EULAR 2004 Germany, Berlin 9-12 June 2004
poster
09.06.2004-12.06.2004
Berlin, Njemačka