engleski

Solvent and temperature effects in Pi-route cyclization

Endo-Bicyclo[3.3.1]non-6-ene-3-carboxylic acid (1) was prepared and the solvent and temperature effects on the pi-route cyclization were studied. The stereochemistry of the products strongly depends on the reaction temperature and the solvent used. The interpretation of the mechanism and product distribution based on experimental data is supported by theoretical investigation.

cyclization ; bicyclo[3.3.1]non-6-ene-3-carbocyclic acid ; 4-chloro-2-adamantanone ; semiempirical methods ; optimization

nije evidentirano