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Pregled bibliografske jedinice broj: 183003

RNA methylation and antibiotic resistance: an overview


Maravić, Gordana; Flögel, Mirna
RNA methylation and antibiotic resistance: an overview // Periodicum biologorum, 106 (2004), 2; 135-140 (međunarodna recenzija, pregledni rad, znanstveni)


CROSBI ID: 183003 Za ispravke kontaktirajte CROSBI podršku putem web obrasca

Naslov
RNA methylation and antibiotic resistance: an overview

Autori
Maravić, Gordana ; Flögel, Mirna

Izvornik
Periodicum biologorum (0031-5362) 106 (2004), 2; 135-140

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, pregledni rad, znanstveni

Ključne riječi
macrolide antibiotics; aminoglycoside antibiotics; antibiotic resistance; RNA methylation; Erm methyltransferases; Agr methyltransferases; inhibitors

Sažetak
Human efforts to efficiently treat the infectious diseases have been seriously threatened by the emergence and spreading of multiply resistant bacterial pathogens. Being one of the top priorities of public health, the restoration of antibiotic arsenal requires a thorough understanding of molecular mechanisms of antibiotic action and resistance. Here we discuss the molecular mechanisms of antibiotic resistance, putting them in perspective with the common processes of RNA modifications. We review the recent data on the bacterial resistance to macrolide-lincosamide-streptogramin B and aminoglycoside antibiotics based on the action of ribosomal RNA methyltransferases from Erm (Erythromycin resistance methylase) and Agr (Aminoglycoside resistance) family. In light of present information, we revisit the existing and propose new directions to combat resistance and to overcome this burning medical problem.

Izvorni jezik
Engleski

Znanstvena područja
Biologija



POVEZANOST RADA


Projekti:
0006611

Ustanove:
Farmaceutsko-biokemijski fakultet, Zagreb

Citiraj ovu publikaciju

Maravić, Gordana; Flögel, Mirna
RNA methylation and antibiotic resistance: an overview // Periodicum biologorum, 106 (2004), 2; 135-140 (međunarodna recenzija, pregledni rad, znanstveni)
Maravić, G. & Flögel, M. (2004) RNA methylation and antibiotic resistance: an overview. Periodicum biologorum, 106 (2), 135-140.
@article{article, year = {2004}, pages = {135-140}, keywords = {macrolide antibiotics, aminoglycoside antibiotics, antibiotic resistance, RNA methylation, Erm methyltransferases, Agr methyltransferases, inhibitors}, journal = {Periodicum biologorum}, volume = {106}, number = {2}, issn = {0031-5362}, title = {RNA methylation and antibiotic resistance: an overview}, keyword = {macrolide antibiotics, aminoglycoside antibiotics, antibiotic resistance, RNA methylation, Erm methyltransferases, Agr methyltransferases, inhibitors} }
@article{article, year = {2004}, pages = {135-140}, keywords = {macrolide antibiotics, aminoglycoside antibiotics, antibiotic resistance, RNA methylation, Erm methyltransferases, Agr methyltransferases, inhibitors}, journal = {Periodicum biologorum}, volume = {106}, number = {2}, issn = {0031-5362}, title = {RNA methylation and antibiotic resistance: an overview}, keyword = {macrolide antibiotics, aminoglycoside antibiotics, antibiotic resistance, RNA methylation, Erm methyltransferases, Agr methyltransferases, inhibitors} }

Časopis indeksira:


  • Web of Science Core Collection (WoSCC)
    • Science Citation Index Expanded (SCI-EXP)
    • SCI-EXP, SSCI i/ili A&HCI
  • Scopus


Uključenost u ostale bibliografske baze podataka:


  • ASFA: Aquatic Science and Fisheries Abstracts
  • Excerpta Medica





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