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Pregled bibliografske jedinice broj: 181583

Maternal and neonatal lymphocyte subpopulations at delivery and 3 days postpartum: increased coexpression of CD45 isoforms


Juretić, Emilja; Gagro, Alenka; Vukelić, Vesna; Petrovečki, Mladen
Maternal and neonatal lymphocyte subpopulations at delivery and 3 days postpartum: increased coexpression of CD45 isoforms // American journal of reproductive immunology, 52 (2004), 1; 1-7 (međunarodna recenzija, članak, znanstveni)


CROSBI ID: 181583 Za ispravke kontaktirajte CROSBI podršku putem web obrasca

Naslov
Maternal and neonatal lymphocyte subpopulations at delivery and 3 days postpartum: increased coexpression of CD45 isoforms

Autori
Juretić, Emilja ; Gagro, Alenka ; Vukelić, Vesna ; Petrovečki, Mladen

Izvornik
American journal of reproductive immunology (1046-7408) 52 (2004), 1; 1-7

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
Lymphocyte immunophenotype; newborns; parturient women; vaginal delivery

Sažetak
PROBLEM: Huge physiologic changes during parturition involve immune cells. Alterations in maternal and neonatal lymphocytes postpartum might ascertain the subpopulations that are most affected and may possibly be of importance in the process. METHOD OF STUDY: Peripheral blood was taken from 20 healthy women at vaginal delivery and 3 days later, concomitantly with cord and peripheral blood from their newborns. Lymphocyte immunophenotyping was done by three-color flow-cytometry. RESULTS: Maternal T helper cells were decreased and natural killer (NK) cells were significantly increased during labor. Percentage of CD4+ and percentage and absolute count of CD8+ cells coexpressing CD45RA and CD45RO antigens were higher than 3 days later. In cord blood NK cells were considerably increased and more CD4+ cells expressed CD45RO antigen. CONCLUSION: Coexpression of CD45RA and CD45RO molecules indicates activation of maternal CD4+ and CD8+ lymphocytes. NK cells increase suggests their possible association with parturition processes. Lymphocyte subsets in cord blood correspond to maternal subsets to some extent.

Izvorni jezik
Engleski

Znanstvena područja
Temeljne medicinske znanosti, Kliničke medicinske znanosti



POVEZANOST RADA


Projekti:
0021001
0021004
0214204

Ustanove:
Imunološki zavod d.d.,
Klinički bolnički centar Zagreb

Profili:

Avatar Url Emilja Juretić (autor)

Avatar Url Mladen Petrovečki (autor)

Avatar Url Alenka Gagro (autor)


Citiraj ovu publikaciju:

Juretić, Emilja; Gagro, Alenka; Vukelić, Vesna; Petrovečki, Mladen
Maternal and neonatal lymphocyte subpopulations at delivery and 3 days postpartum: increased coexpression of CD45 isoforms // American journal of reproductive immunology, 52 (2004), 1; 1-7 (međunarodna recenzija, članak, znanstveni)
Juretić, E., Gagro, A., Vukelić, V. & Petrovečki, M. (2004) Maternal and neonatal lymphocyte subpopulations at delivery and 3 days postpartum: increased coexpression of CD45 isoforms. American journal of reproductive immunology, 52 (1), 1-7.
@article{article, year = {2004}, pages = {1-7}, keywords = {Lymphocyte immunophenotype, newborns, parturient women, vaginal delivery}, journal = {American journal of reproductive immunology}, volume = {52}, number = {1}, issn = {1046-7408}, title = {Maternal and neonatal lymphocyte subpopulations at delivery and 3 days postpartum: increased coexpression of CD45 isoforms}, keyword = {Lymphocyte immunophenotype, newborns, parturient women, vaginal delivery} }
@article{article, year = {2004}, pages = {1-7}, keywords = {Lymphocyte immunophenotype, newborns, parturient women, vaginal delivery}, journal = {American journal of reproductive immunology}, volume = {52}, number = {1}, issn = {1046-7408}, title = {Maternal and neonatal lymphocyte subpopulations at delivery and 3 days postpartum: increased coexpression of CD45 isoforms}, keyword = {Lymphocyte immunophenotype, newborns, parturient women, vaginal delivery} }

Časopis indeksira:


  • Current Contents Connect (CCC)
  • Web of Science Core Collection (WoSCC)
    • Science Citation Index Expanded (SCI-EXP)
    • SCI-EXP, SSCI i/ili A&HCI
  • Scopus
  • MEDLINE





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