engleski

Octeotride for acute esophageal variceal bleeding.

The aim of the present study was to compare the efficacy of endoscopic variceal sclerotherapy alone and in combination with octeotride in the treatment of acute variceal bleeding. A total of 60 patinets were included in the study. The patients were divided into two groups: group A- 30 patients treated only with sclerotherapy and group B- 30 patients treated with sclerotherapy plus octeotride in continous infusion. The effect variables were: duration of hospital stay, number of blood transfusions, mean hemoglobin levels afted tretment, number with rebleeding, and mortality in the firs six days. Two treatment groups were similar with regrad to the etiology of portal hypertension, Child's class, age and clinical characteristics. The patinets were evaluated after 48 hours and after six days of treatment. In group B blood loos, transfusions requirements, rebleeding episodes, mortality and mean hospital stay were significantly reduced. The combination of sclerotherapy plus octeotride in the treatment of acute variceal bleeding is more effective then sclerotherapy alone.

esophageal varices; sclerotherapy; octreotide.

nije evidentirano