Genetic Instabilities of the E-cadherin gene (CDH1) in renal cell carcinoma (CROSBI ID 502773)
Prilog sa skupa u zborniku | sažetak izlaganja sa skupa | međunarodna recenzija
Podaci o odgovornosti
Pećina-Šlaus, Nives ; Gall-Trošelj, Koraljka ; Radić, Krešimir ; Pavelić, Krešimir ; Pavelić, Jasminka
engleski
Genetic Instabilities of the E-cadherin gene (CDH1) in renal cell carcinoma
The role of tumor suppressor gene E-cadherin, CDH1 was investigated in renal cell carcinoma (RCC). D16S752 marker linked to E-cadherin gene (informativeness 91%) revealed 3 (7, 5%) LOH cases. Interestingly, in 9.1% of RCC samples replication error phenotype (RER+) was detected. Our results suggest that alterations in E-cadherin gene, are involved in evolution and progression of RCC. Microsatellite genetic instability of the E-cadherin gene indicates that another cellular mechanism, mismatch repair, may also be targeted in RCC.
E-cadherin gene; RCC; LOH
nije evidentirano
nije evidentirano
nije evidentirano
nije evidentirano
nije evidentirano
nije evidentirano
Podaci o prilogu
2001.
objavljeno
Podaci o matičnoj publikaciji
Abstracts of the The 12th Ljudevit Jurak International Symposium on Comparative Pathology
Zagreb:
Podaci o skupu
Ljudevit Jurak International Symposium on Comparative Pathology (12 ; 2001)
ostalo
01.06.2001-02.06.2001
Zagreb, Hrvatska
