engleski

Pancreatic Neuroendocrine Tumor presenting with carcinoid syndrome : Case report

Carcinoid is the most common neuroendocrine tumor. It is primarily localized in the ileum and the appendix, whereas other localizations are rare. Only a small number of the carcinoids present with carcinoid syndrome, (flushing.diarrhea), usually after tumor has already metastasized. A case of carcinoid tumor of uncommon localization is reported. A 54-year-old male patient presented for evaluation because of weight loss, flushing and diarrhea. Laboratory value of 5-HIAA was 775.5 mmol/l (normal values up to 72.8) and the pancreatic tumor marker CA l9-9 was increased. Ultrasonografic and magnetic resonance findings localized the tumor in the prepapillary pancreatic region and visualized the spread to the liver. The diagnosis was confirmed by pathohistologic evaluation of a liver biopsy specimen. The patient was treated with Sandostatin (octreotide analog), which led to significant relief of the symptoms, although control 5-HIAA values were not reduced.

Neuroendocrine tumors; diagnosis; Pancreatic neoplasm; diagnosis; Pancreatic neoplasms; drug therapy; Carcinoid tumor; diagnosis; Carcinoid tumor; drug therapy; Case report

nije evidentirano