engleski

Duration of diabetes mellitus and occurence of ischemic stroke

The aim of study was to determine a possible association between the duration of diabetes mellitus and occurrence of ischemic stroke. Study group consisted of 429 patients hospitalized at our department for ischemic stroke during 12 consecutive months. The diagnosis and type of diabetes were established on the basis of pre-stroke history dana and confirmed by consultant diabetologist. Hyperglycemia was reciorded in 95 patients with ischemic stroke (22, 1%), 72 of them had the diagnosis of diabetes mellitus established prior to stroke (type 1 in nine, and type 2 in 63 patients). There were 53 females and 42 males, mean age 68.6 7.8 years. Diabetes of 6 or more years of duration was associated with a higher rate of ischemic stroke than the shorter diabetes duration of up to 5 years (50 vs 22 patients). Further analysis revealed a significant differrence in stroke prevalence between the patients with type 2 diabetes duration of 6-10 and 11 years and more (p less 0.01) ; in the group of patients with longest diabetes duration, the presence of this disease facilitated the occurrence of stroke. The functional outcome of stroke as assessed by the Modified Rankin Scale showed a more severe functional deficit in the group of patients with hyperglicemia than in the group of ischemic stroke patients without it. Prolonged duration of diabetes had greater impact on the occurrence of stroke than shorter duration of the disease. The presence of hyperglycemia in the acute phase of stroke aggravates the final outcome of ischemic stroke.

diabetes mellitus; duration; stroke

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