hrvatski

Antimicrobial activity of genius Satureja essential oils

Essential oils of plants and their components, products from the secondary metabolism of a plant, have many applications in folk medicine, food flavoring and preservation as well as in pharmaceutical industries. The phytochemical GC/MS analysis and in vitro antimicrobial activity of the essential oils in aerial parts of Satureja montana L. (Winter savory) and Satureja cuneifolia Ten., collected in the littoral part of submediterranean region of Croatia, were performed. The major compound of S. montana oil was phenolic monoterpene carvacrol (45.7%). Other important compounds were monoterpenic hydrocarbons p-cymene (12.6%), γ -terpinene (8.1%) and oxygen-containing compounds carvacrol methyl ether, borneol, thymol and thymol methyl ether. The volatile oil of S. cuneifolia was characterized with β -cubebene (8.7%), limonene (8.3%), α -pinene (6.9%), spathulenol and β -caryophyllene. The antimicrobial activity of oils was evaluated by broth microdilution method. Using a panel witch included clinical pathogens and laboratory control strains such as Bacillus subtilis, Enterococcus faecium, Staphylococcus aureus, Pseudomonas aeruginosa, Serratia marcescens, Esherichia coli, Candida albicans, Saccharomyces cerevisiae and Aspergillus fumigatus. All strains used for the tests, excepted for B. subtilis and E. coli were resistant to at least one know antimicrobial agents. The antimicrobial effects of S. montana and S. cuneifolia oils were active against all the test strains with the exception of P. aeruginosa. The oil of S. montana exhibited greater antimicrobial activity than the oil of S. cuneifolia. Maximum activity of S. montana oil was observed against E. coli, methicillin-resistant S. aureus and against yeast (Candida albicans). The essential oil of S. cuneifolia was also found to inhibit the growth of medically important pathogens such as S. aureus and E. coli. The fungicidal activity in both oils against C. albicans and S. cerevisiae was also observed. We conclude that investigated oils can be safely used as a complementary therapy of systematic infection.

Satureja; eterična ulja; antimikrobna aktivnost

nije evidentirano

engleski

Antimicrobial activity of genius Satureja essential oils

Essential oils of plants and their components, products from the secondary metabolism of a plant, have many applications in folk medicine, food flavoring and preservation as well as in pharmaceutical industries. The phytochemical GC/MS analysis and in vitro antimicrobial activity of the essential oils in aerial parts of Satureja montana L. (Winter savory) and Satureja cuneifolia Ten., collected in the littoral part of submediterranean region of Croatia, were performed. The major compound of S. montana oil was phenolic monoterpene carvacrol (45.7%). Other important compounds were monoterpenic hydrocarbons p-cymene (12.6%), γ -terpinene (8.1%) and oxygen-containing compounds carvacrol methyl ether, borneol, thymol and thymol methyl ether. The volatile oil of S. cuneifolia was characterized with β -cubebene (8.7%), limonene (8.3%), α -pinene (6.9%), spathulenol and β -caryophyllene. The antimicrobial activity of oils was evaluated by broth microdilution method. Using a panel witch included clinical pathogens and laboratory control strains such as Bacillus subtilis, Enterococcus faecium, Staphylococcus aureus, Pseudomonas aeruginosa, Serratia marcescens, Esherichia coli, Candida albicans, Saccharomyces cerevisiae and Aspergillus fumigatus. All strains used for the tests, excepted for B. subtilis and E. coli were resistant to at least one know antimicrobial agents. The antimicrobial effects of S. montana and S. cuneifolia oils were active against all the test strains with the exception of P. aeruginosa. The oil of S. montana exhibited greater antimicrobial activity than the oil of S. cuneifolia. Maximum activity of S. montana oil was observed against E. coli, methicillin-resistant S. aureus and against yeast (Candida albicans). The essential oil of S. cuneifolia was also found to inhibit the growth of medically important pathogens such as S. aureus and E. coli. The fungicidal activity in both oils against C. albicans and S. cerevisiae was also observed. We conclude that investigated oils can be safely used as a complementary therapy of systematic infection.

Satureja; essential oils; antimicrobial activity

nije evidentirano