engleski

Female genital HPV infection in Požega region

Evidence collected in the last 30 years indicates that female genital HPV infection correlates with a vast majority of cervical intraepithelial lesions and almost all-invasive carcinomas. These findings suggest that conventional cervical cancer screening using Pap smears could be improved by HPV testing. Based on these facts, the importance of detection of HPV infection of lower genital tract is easily understandable as well as proper monitoring of HPV positive women. Between May 2001 and December 2003, 190 women with mostly abnormal Pap smear were admitted for examination, testing and treatment in the Gynecological polyclinic of Požega of County General Hospital. In each women endocervical cyto-brush was taken for HPV DNA identification by polymerase chain reaction (PCR), as well as endocervical smear for microbiological analysis of Chlamydia trachomatis, Mycoplasma hominis, Ureaplasma urealyticum, Trichomonas vaginalis and other bacteria. Among women with abnormal Pap smear in Požega region, more than half was HPV positive. Single HPV infection was commonly identified, of which HPV16 was the most frequently found (>1/3 cases). The frequency of HPV infection increases accordingly with cytological abnormalities and decrease with age. Almost 1/3 of tested women was nuliparous, but HPV infection was not significantly higher among them. Moreover, almost 2/3 of women had microbiological (C. trachomatis, M. hominis, U. urealyticum, T. vaginalis and/or other) positive endocervical smear, of which more than half were also HPV positive.

genital infection

nije evidentirano