engleski

Predictive Value of APACHE II and SAPS Scores for Development of Complications in Acute Pancreatitis

Grading of severity is important in providing appropriate therapy for acute pancreatitis. We compared values of APACHE II and SAPS scores with Ranson score in prediction of local and systemic complications in patients with acute pancreatitis. We undertook a prospective study of 242 patients with diagnosis of acute pancreatitis admitted to our hospital during past four years. The inclusion criteria consisted of combination of clinical features, a typical case history, elevation of serum pancreatic enzymes and diagnosis confirmed by imaging studies (US or CT). In all patients severity criteria were noted using Ranson scores and compared with APACHE II and SAPS scores on first and third day after admission. Cut off values for predicting complications were 3 for Ranson, 8 for APACHE II and 18 for SAPS score. Ranson score has specificity of 64, 82% and sensitivity of 36, 89% in predicting complications in our group of patients, while APACHE II score has lower specificity (69, 39%, 70, 33%) and low sensitivity (20% and 50% respectively) on first and third day. Also, SAPS score has lower sensitivity, (29, 81%, 31, 25%) and high specificity on first and highest on third day (69, 13% and 76, 47% respectively). Scoring systems used for predicting development of complications in patients with acute pancreatitis in our study showed relatively low diagnostic accuracy (DA). The best DA was shown for APACHE II on 3rd day after admission (69, 83%) while DA for Ranson score was 58, 68%.

acute pancreatitis; APACHE II; SAPS; complications

ISBN 953-6451-21-2 ; Rad je kao poster prezentiran i ns skupu 10. godišnji sastanak Hrvatskog gastroenterološkog društva, odrzanom od 04.-06. 11. 2004., Bizovačke toplice, Hrvatska.