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Pregled bibliografske jedinice broj: 160964

Accumulation Dynamics of the Brain Total Free Fatty Acids and Free Arachidonic Acid in the Models of Cerebral Hypoxia and Epilepsy in Rats


Župan, Gordana; Varljen, Jadranka; Eraković, Vesna; Mršić, Jasenka; Križ, Jasna; Simonić, Ante; Milin, Čedomila
Accumulation Dynamics of the Brain Total Free Fatty Acids and Free Arachidonic Acid in the Models of Cerebral Hypoxia and Epilepsy in Rats // Croatica chemica acta, 68 (1995), 3; 485-490 (međunarodna recenzija, članak, znanstveni)


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Naslov
Accumulation Dynamics of the Brain Total Free Fatty Acids and Free Arachidonic Acid in the Models of Cerebral Hypoxia and Epilepsy in Rats

Autori
Župan, Gordana ; Varljen, Jadranka ; Eraković, Vesna ; Mršić, Jasenka ; Križ, Jasna ; Simonić, Ante ; Milin, Čedomila

Izvornik
Croatica chemica acta (0011-1643) 68 (1995), 3; 485-490

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
free fatty acids; free arachidonic acid; cerebral hypoxia; epilepsy; rats

Sažetak
The aim of this study was to determine the dynamics of the brain free fatty acid (FFA) pool in rats exposed to: a) controlled hypoxia and b) experimental epilepsy. Animals from group a) were subjected to hypoxia procedure. Immediately, 5, 15 or 60 minutes after loosing the righting reflex, the animals were decapitated and brains were quickly removed. Animals from group b) received penicillin (500 U/5 ul) into the left lateral ventricle and were decapitated immediately, 5 or 15 minutes after the appearance of epileptic seizures. The FFA were quantified by gas chromatography. An increase in the total brain FFA content with the maximum level at 60 minutes after losing the righting reflex was detected in hypoxia-exposed rats. The highest level of the brain free arachidonic acid (FAA) was detected 15 minutes after hypoxia. Seizures also produced an increase in the total brain FFA and brain FAA, with a statistically significant level 5 minutes after the appearance of epileptic seizures.

Izvorni jezik
Engleski

Znanstvena područja
Temeljne medicinske znanosti



POVEZANOST RADA


Ustanove:
Medicinski fakultet, Rijeka


Citiraj ovu publikaciju

Župan, Gordana; Varljen, Jadranka; Eraković, Vesna; Mršić, Jasenka; Križ, Jasna; Simonić, Ante; Milin, Čedomila
Accumulation Dynamics of the Brain Total Free Fatty Acids and Free Arachidonic Acid in the Models of Cerebral Hypoxia and Epilepsy in Rats // Croatica chemica acta, 68 (1995), 3; 485-490 (međunarodna recenzija, članak, znanstveni)
Župan, G., Varljen, J., Eraković, V., Mršić, J., Križ, J., Simonić, A. & Milin, Č. (1995) Accumulation Dynamics of the Brain Total Free Fatty Acids and Free Arachidonic Acid in the Models of Cerebral Hypoxia and Epilepsy in Rats. Croatica chemica acta, 68 (3), 485-490.
@article{article, year = {1995}, pages = {485-490}, keywords = {free fatty acids, free arachidonic acid, cerebral hypoxia, epilepsy, rats}, journal = {Croatica chemica acta}, volume = {68}, number = {3}, issn = {0011-1643}, title = {Accumulation Dynamics of the Brain Total Free Fatty Acids and Free Arachidonic Acid in the Models of Cerebral Hypoxia and Epilepsy in Rats}, keyword = {free fatty acids, free arachidonic acid, cerebral hypoxia, epilepsy, rats} }
@article{article, year = {1995}, pages = {485-490}, keywords = {free fatty acids, free arachidonic acid, cerebral hypoxia, epilepsy, rats}, journal = {Croatica chemica acta}, volume = {68}, number = {3}, issn = {0011-1643}, title = {Accumulation Dynamics of the Brain Total Free Fatty Acids and Free Arachidonic Acid in the Models of Cerebral Hypoxia and Epilepsy in Rats}, keyword = {free fatty acids, free arachidonic acid, cerebral hypoxia, epilepsy, rats} }

Časopis indeksira:


  • Current Contents Connect (CCC)
  • Web of Science Core Collection (WoSCC)
    • SCI-EXP, SSCI i/ili A&HCI





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