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Atypical disseminated canine histoplasmosis - a case report (CROSBI ID 107768)

Prilog u časopisu | izvorni znanstveni rad | međunarodna recenzija

Džaja, Petar ; Grabarević, Željko ; Rakočević, Silvija ; Gudan, Andrea ; Beck, Ana ; Smolec, Ozren ; Sabočanec, Ružica Atypical disseminated canine histoplasmosis - a case report // Veterinarski arhiv, 74 (2004), 2; 165-173

Podaci o odgovornosti

Džaja, Petar ; Grabarević, Željko ; Rakočević, Silvija ; Gudan, Andrea ; Beck, Ana ; Smolec, Ozren ; Sabočanec, Ružica

engleski

Atypical disseminated canine histoplasmosis - a case report

The paper describes a case of disseminated histoplasmosis in a 13-year-old female, mixed-breed dog, which was suffered from severe atopyc dermatitis which was treated with prednisolone. Blood laboratory evaluation showed anaemia, decreased hemoglobin level, decreased PCV, and blood smear examination revealed lymphopenia and neutrofilic left shift. Because of the poor health condition the animal was euthanised and necropsy was performed at our department. Macroscopically, deep hemorrhagic bilateral necrosis on both coxal tubers, miliary necroses dispersed through the liver, severe subcutaneous oedema and diffusely enlargement of spleen and lymp nodes were found. Tissue samples for histopathological examination were stained using hematoxiline-eosine method, PAS stain and Grocott's methamine silver method for fungi. Histopathological examination of skin lesion, liver, spleen and lymph nodes revealed numerous enlarged histiocytes infiltrated with inztracytoplasmatical oval, 2-4 μ m large yeastlike bodies. This intramacrophagic yeast was identified as fungus Histoplasma capsulatum and to our knowledge this is the first case of histoplasmosis in Croatia. The way of infection was very likely transepidermal through preexisting skin lesions caused by atopy, because the lungs and intestines were without any sign of histoplasmosis.

histoplazma capsulatum ; disseminated histoplasmosis ; dog ; Croatia

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Podaci o izdanju

74 (2)

2004.

165-173

objavljeno

0372-5480

1331-8055

Povezanost rada

Veterinarska medicina

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