engleski

The modified procedure for beta-1, 3-glucan isolation from brewer^, s yeast

Beta-glucans, glucose polymers with numerous health benefits, are found in yeast, certain mushrooms and in the bran of oats and barley. Beta-glucans act as biological response modifiers (BRM, s) that take active part in regulation of immune system, modulation of inflammation in wound healing, regeneration of tissue and in lowering of blood cholesterol. They could find wide application in human and veterinary medicine, as well as in cosmetic, food and feed production. Beta-1, 3-glucan derived from the cell wall of yeast Saccharomyces cerevisiae has been reported to produce the highest biological effects. It is safe (GRAS status given by FDA), natural and highly effective. The aim of this work was to find the appropriate and effective extraction procedure for its isolation from brewer, s yeast, a by-product in beer production. The extraction method involved stripping away various layers of carbohydrates, proteins, lipids and other material that make up a yeast cell. Many steps such as yeast sieving, debittering by alkaline wash, autolysis, alkaline and acid extractions and alcohol treatment were used in isolation procedure.

beta-1; 3-glucan; brewer^; s yeast; Saccharomyces cerevisiae

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