engleski

Synthesis of glucoconjugates with heterocyclic oximes

The syntheses of perpivaloylated N- glucoconjugates have been reported. The glucose derivative, tetra-O-pivaloyl-alpha-D- glucopyranosyl bromide, was conected with three different heterocyclic oximes: 3- hydroxyiminoquinuclidine, 4- hydroxyiminomethylpyridine and N-methyl-2- hydroxyiminomethylimidazole. All synthesized N- glucoconjugates were beta anomers as proved by NMR spectra. Structures of synthesized N- glucoconjugates were established by spectroscopy (IR, MS, 1D and 2D NMR), elemental analyses and optical rotations measurements.

glucoconjugates ; heterocyclic oximes

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