engleski

Synthesis of a new Macrocyclic Polythiaether-Diester Ligands

In recent years considerable effort has been made to design syntetic complexing agents, for metal ions and charged molecules. Thiacrown ethers have been studied chiefly for their capacity to ligate transition metal ions. They bind second- and third- row transiton metal ions and generally stabilize the lower oxidation states of these ions. Various modifications have been made to the basic crown thiaether structures in attempt to enhance the selectivity of these ligands and the stabilities of complex formed. Among these modifications are the inclusion of ester linkages and polycyclic moietys3 in the polyether ring. We describe here the synthesis of several new macrocyclic polythiaether-diester compounds, containing the 1, 3-bridged adamantyl moiety which function as a rigidifying "spacer" and also serves to confer a degree of preorganization upon the macrocyclic thiaether. We also highlight the use of novel family of stannanthianes as activated dithiols for the efficient preparation of macrocyclic thialactones.

macrocycles; crown thiaether

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